Early intubation and decreased in-hospital mortality in patients with coronavirus disease 2019

Table 4 In-hospital mortality in subgroup analyses

	Early intubation	Non-early intubation	OR	95% CI
Age
< 65 years	1.7% (0.0–3.7%)	11.1% (6.1–16.1%)	0.14	0.04–0.50
≥ 65 years	16.7% (11.6–21.9%)	40.0% (33.2–46.8%)	0.30	0.19–0.48
Severity of hypoxemia before intubation
PaO₂ < 60 mm Hg	3.4% (0.1–6.7%)	39.7% (27.6–51.8%)	0.05	0.02–0.16
PaO₂ ≥ 60 mm Hg	12.7% (7.6–17.7%)	26.7% (19.9–33.4%)	0.40	0.23–0.71
Inadequate resuscitation before intubation
Lactate ≤ 2 mmol/L	6.8% (3.7–2.9%)	28.7% (22.0–35.5%)	0.47	0.16–1.37
Lactate > 2 mmol/L	20.0% (5.7–34.3%)	34.7% (21.4–48.0%)	0.18	0.10–0.33
Days from admission to intubation
≤ 2 days	9.5% (6.2–12.7%)	27.9% (22.6–33.2%)	0.27	0.17–0.43
≥ 3 days	12.3% (3.8–20.8%)	26.0% (16.2–35.8%)	0.40	0.16–1.02

Inverse probability weighting analyses were performed in each subgroup and presented as % (95% CI)
OR odds ratio, CI confidence interval, PaO₂ partial pressure of oxygen

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