Table 3 Early intubation and clinical outcomes
From: Early intubation and decreased in-hospital mortality in patients with coronavirus disease 2019
| Â | Early intubation | Non-early intubation | p value | OR (95% CI) | Difference in median (95% CI) |
|---|---|---|---|---|---|
In-hospital mortality | Â | Â | Â | Â | Â |
 Unadjusted, n/total (%) | 18/110 (16.4%) | 87/302 (28.8%) | 0.010 | 0.48 (0.28–0.85) |  |
 IPW analysis, % (95% CI) | 9.9% (6.9–12.9%) | 27.6% (22.9–32.2%) | < 0.001 | 0.29 (0.19–0.44) |  |
Hospital-free days to day 30 after intubation, days, median (IQR) | 23 (16–27) | 14 (0–25) | < 0.001 |  | 3 (1–5) |
Ventilator-free days to day 30 after intubation, days, median (IQR) | 5 (0–14) | 1 (0–15) | 0.010 |  | 0 (0–2) |
Requirement of prone ventilation, % (95% CI) | 28.8% (23.8–33.8%) | 33.4% (28.3–38.6%) | 0.206 | 0.81 (0.58–1.13) |  |
Requirement of ECMO, % (95% CI) | 1.6% (0.3–2.9%) | 14.4% (10.8–18.1%) | < 0.001 | 0.10 (0.04–0.23) |  |
Re-intubation, % (95% CI) | 10.6% (7.3–14.0%) | 7.7% (4.3–11.2%) | 0.244 | 1.42 (0.78–2.58) |  |
Nosocomial infection of COVID-19 due to HFNC/NIPPV, per institution, n/total (%) | Â | Â | Â | Â | Â |
 Pre-intubation usage |  | 0/16 (0.0%) |  |  |  |
 Post-intubation usage | 0/2 (0.0%) | 0/5 (0.0%) |  |  |  |