Table 1 Basic data on the studied subjects and data from the experiments

N

15

15

15

10

15

Age (years)

31 (12)

45 (15)

46 (15)

66 (9)^a

65 (13)^a

Body weight (kg)

73 (14)

95 (17)^a

72 (16)

79 (8)

73 (13)

Females/males

6/9

3/12

10/5

2/8

2/13

Infused fluid volume (mL)

229 (39)

281 (56)

216 (48)

238 (24)

218 (42)

P-albumin (g/L), baseline

41 (3)

24 (5)^a

37 (2)

34 (4)

25 (5)^a

MAP (mmHg), baseline

93 (6)

87 (1)

65 (6)

78 (6)

75 (8)

C-reactive protein (mg/L)

2 (3)

86 (20–294)

< 5^b

62 (54–167)^c

61 (21–216)

‘Inflammation’

No

Yes

No

Possible

Yes

Blood loss (mL)

140

140

340 (190–1340)

940 (640–1840)

None

P-creatinine (µmol/L)

78 (20)

78 (13)

71 (10)

105 (8)

67 (11)

Maximum P-dilution (%)

14.2 (4.8)

16.3 (6.0)

13.6 (5.6)

8.3 (5.6)^d

13.3 (4.9)

Reference number

9, 10

10

11

12

9