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Fig. 5 | Critical Care

Fig. 5

From: Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials

Fig. 5

Organ failure and mortality curves over 28 days among 24-h phenotypes. Number of organ failures and mortality according to PedSep-A, B, C, and D phenotype over 28 days. Both short-term mortality (panel A) and organ failure (panel B) show significant differences by phenotype (p < 0.001). The mean numbers of organ failures and 95% confidence intervals (CI) are calculated each day by non-nested observation, where we do not carry forward the OFI at the time the patient leaves the PICU alive or dead. As a reference for patients at risk for Panel B, Panel C shows the number of children remaining in the PCU at day 0, 7, 14, 21, and 28

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Critical Care

ISSN: 1364-8535