Skip to main content

Table 2 Comparison study general estimating equations model for “any treatment limitation or no treatment limitation”

From: Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill

 

Estimate

OR

95% CI

P value

Lower

Upper

Ethicus 2 study (2015–2016) vs. Ethicus 1 study (1999–2000)

3.59

36.29

9.12

144.47

 < 0.001

Region

     

 Central Europe vs. Northern Europe

− 0.20

0.82

0.42

1.59

0.56

 Southern Europe vs. Northern Europe

− 1.13

0.32

0.15

0.68

0.003

Age

0.03

1.02

1.02

1.03

 < 0.001

Sex, female vs. male

− 0.02

0.98

0.89

1.07

0.62

Physician religion

     

 Catholic vs. none

0.64

1.89

1.19

3.00

0.007

 Jewish vs. none

1.04

2.83

1.48

5.41

0.002

 Greek orthodox vs. none

0.55

1.74

0.97

3.10

0.06

 Protestant vs. none

0.87

2.39

1.42

4.04

0.001

 Unknown vs. none

− 6.03

0.002

0.001

0.010

< 0.001

 Other vs. none

0.26

1.30

0.75

2.25

0.35

 Islam vs. none

0.41

1.51

0.63

3.60

0.35

Acute diagnoses

     

 Surgery vs. neurologic

− 0.13

0.88

0.62

1.23

0.45

 Respiratory vs. neurologic

0.49

1.64

1.16

2.32

0.006

 Cardiovascular vs. neurologic

− 0.19

0.83

0.62

1.11

0.22

 Gastrointestinal vs. neurologic

0.68

1.98

1.40

2.81

 < 0.001

 Metabolic vs. neurologic

0.70

2.01

1.00

4.06

0.0502

 Hematologic vs. neurologic

0.48

1.62

0.71

3.74

0.26

 Trauma vs. neurologic

− 0.32

0.73

0.51

1.05

0.09

 Sepsis vs. neurologic

0.65

1.92

1.25

2.94

0.003

 Other vs. neurologic

0.51

1.66

1.00

2.74

0.048

Chronic diseases

     

 Cardiovascular diseases vs. none

0.56

1.75

1.40

2.18

 < 0.001

 Neurological-cognitive diseases–muscular vs. none

0.74

2.09

1.25

3.48

0.005

 Chest diseases vs. none

0.91

2.48

1.80

3.40

 < 0.001

 Kidney and urinary system diseases vs. none

0.38

1.47

0.88

2.44

0.14

 Digestive system vs. none

1.49

4.46

2.72

7.29

 < 0.001

 Immunologic system vs. none

0.93

2.53

1.49

4.30

0.001

 General history vs. none

0.43

1.54

1.14

2.07

0.005

 Cancer vs. none

1.17

3.23

2.15

4.83

 < 0.001

 Unknown vs. none

1.30

3.67

1.56

8.65

0.003

End-of-life practice variables

     

 Routine ICU family meetings: yes vs. no

− 0.03

0.97

0.52

1.79

0.91

 Daily deliberation for appropriate level of ICU care: yes vs. no

0.57

1.77

0.96

3.28

0.07

 End-of-life (EOL) discussions during weekly (family) meetings: yes vs. no

− 0.61

0.55

0.30

0.99

0.047

 Written triggers for limitations: yes vs. no

-0.14

0.87

0.41

1.86

0.72

 Written ICU EOL guidelines: yes vs. no

− 0.65

0.52

0.31

0.87

0.013

 Written ICU EOL protocols: yes vs. no

2.71

15.08

3.88

58.59

 < 0.001

 Palliative care consultations: yes vs. no

0.97

2.63

1.23

5.60

0.012

 Ethics consultations: yes vs. no

− 0.96

0.38

0.14

1.07

0.07

 ICU staff taking communication courses: yes vs. no

0.13

1.14

0.52

2.51

0.74

 ICU staff taking bioethics courses: yes vs. no

− 0.19

0.83

0.19

3.57

0.80

 Country EOL guidelines: yes vs. no

0.14

1.16

0.53

2.50

0.72

 Country EOL legislation: yes vs. no

1.17

3.24

1.60

6.55

0.001

 Intercept

− 1.54

0.21

0.08

0.59

0.003

  1. Patient data originate from the entire comparison study population (n = 4592) (4)
  2. CI confidence interval, OR odds ratio. Collinearity assessment: variance inflation, 1.03–4.29; condition index, 30.75
Back to article page

Critical Care

ISSN: 1364-8535