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Table 2 Average effect of CRRT versus IHD on secondary outcomes in the original and inverse probability of treatment weighted samples

From: Continuous renal replacement therapy versus intermittent hemodialysis as first modality for renal replacement therapy in severe acute kidney injury: a secondary analysis of AKIKI and IDEAL-ICU studies

Outcome

CRRT group (n = 269)

IHD group (n = 274)

RR or Difference

(95% CI)

Weighted RR or weighted difference

(95% CI)

Hospital mortality

146 (54.2%)

132 (48.3%)

1.12

(0.95 to 1.32)

1.13

(0.94 to 1.34)

ICU mortality

130 (48.3%)

114 (41.6%)

1.16

(0.96 to 1.40)

1.14

(0.93 to 1.39)

Survival with no RRT dependence at day 28

117 (43.5%)

132 (48.0%)

0.91

(0.75 to 1.10)

0.92

(0.75 to 1.13)

Kidney recovery at day 28

123 (45.7%)

134 (48.9%)

0.93

(0.78 to 1.12)

1.00

(0.83 to 1.21)

RRT-free days at day 28

11.5 (12.0)

13.4 (12.6)

− 1.9

(− 3.9 to 0.2)

− 1.6

(− 3.9 to 0.4)

Ventilator-free days at day 28

8.0 (10.0)

9.9 (10.8)

− 1.9

(− 3.7 to − 0.2)

− 1.9

(− 3.4 to − 0.1)

Vasopressor-free days at day 28

11.6 (11.7)

14.1 (12.3)

− 2.5

(− 4.5 to − 0.5)

− 2.1

(− 4.1 to − 0.1)

ICU-free days at day 28

6.0 (8.6)

7.7 (9.5)

− 1.6

(− 3.2 to − 0.1)

− 1.4

(− 3.1 to 0.2)

Length of ICU stay, days

14.2 (15.4)

14.4 (20.8)

− 0.2

(− 3.8 to 2.5)

0.1

(− 3.0 to 2.6)

  1. Data are mean (SD) or n (%). All results are pooled over the imputed datasets. RRT renal replacement therapy, CRRT continuous renal replacement therapy, IHD intermittent hemodialysis, ICU intensive care unit, RR risk ratio, CI confidence interval