Table 2 Prognostic performance of single prognostic methods as recommended by ERC/ESICM
From: External validation of the 2020 ERC/ESICM prognostication strategy algorithm after cardiac arrest
| Â | N | AUC | Sensitivity | Specificity | TP | TN | FP | FN |
|---|---|---|---|---|---|---|---|---|
A. Unconscious patients at ≥ 72 h after ROSC without confounders | ||||||||
 GCS_M ≤ 3 | 660 | 0.707 (0.644–0.770) | 89.9 (87.3–92.3) | 69.0 (56.9–79.5) | 530 | 49 | 22 | 59 |
 No PR/CR | 518 | 0.661 (0.588–0.734) | 62.9 (58.2–67.4) | 100 (94.9–100) | 281 | 71 | 0 | 166 |
 No SSEP N20 | 150 | 0.864 (0.805–0.923) | 72.7 (64.3–80.1) | 100 (81.5–100) | 96 | 18 | 0 | 36 |
 NSE > 60 | 363 | 0.867 (0.822–0.912) | 78.8 (73.8–83.3) | 94.6 (85.1–98.9) | 242 | 53 | 3 | 65 |
 Highly malignant EEG | 249 | 0.796 (0.741–0.851) | 59.2 (52.2–66.0) | 100 (91.8–100) | 122 | 43 | 0 | 84 |
 Poor CT | 602 | 0.619 (0.564–0.673) | 32.8 (28.7–37.1) | 90.9 (83.4–95.8) | 165 | 90 | 9 | 338 |
 Poor DWI | 332 | 0.890 (0.856–0.924) | 78.0 (72.7–82.7) | 100.0 (92.9–100) | 220 | 50 | 0 | 62 |
B. Unconscious patients with GCS_M ≤ 3 at ≥ 72 h after ROSC without confounders | ||||||||
 No PR/CR | 471 | 0.821 (0.778–0.864) | 64.1 (59.4–68.7) | 100 (91.0–100) | 277 | 39 | 0 | 155 |
 No SSEP N20 | 133 | 0.874 (0.799–0.949) | 74.8 (66.3–82.1) | 100 (54.1–100) | 95 | 3 | 0 | 32 |
 NSE 60 | 319 | 0.905 (0.870–0.939) | 81.0 (76.0–85.3) | 100 (86.3–100) | 238 | 25 | 0 | 56 |
 Highly malignant EEG | 224 | 0.802 (0.738–0.866) | 60.4 (53.3–67.2) | 100 (84.6–100) | 122 | 22 | 0 | 80 |
 Poor CT | 537 | 0.601 (0.527–0.674) | 33.6 (29.4–38.0) | 86.5 (74.2–94.4) | 163 | 45 | 7 | 322 |
 Poor DWI | 298 | 0.897 (0.860–0.934) | 79.5 (74.2–84.1) | 100 (86.3–100) | 217 | 25 | 0 | 56 |