Table 1 Demographic characteristics of subjects according to neurological outcome
From: External validation of the 2020 ERC/ESICM prognostication strategy algorithm after cardiac arrest
|  | Good N = 108 | Poor N = 552 | p |
|---|---|---|---|
Age, median (IQR) | 57 (47–66) | 61 (50–72) | 0.003 |
Sex, male | 88 (81.5) | 362 (65.6) | 0.001 |
Past history | Â | Â | Â |
 HTN | 37 (34.3) | 319 (39.7) | 0.291 |
 DM | 22 (20.4) | 157 (28.4) | 0.084 |
CA place, residence, yes | 41 (38.0) | 313 (56.7) |  < 0.001 |
Witnessed arrest, no. (%) | 84 (77.8) | 312 (56.5) |  < 0.001 |
Bystander CPR, no. (%) | 72 (66.7) | 327 (59.2) | 0.149 |
Shockable rhythm, no. (%) | 71 (65.7) | 90 (16.3) |  < 0.001 |
Cardiac cause of arrest, no. (%) | 93 (86.1) | 253 (45.8) |  < 0.001 |
Minutes to ROSC, median (IQR) | 16.0 (10.5–19.0) | 29.0 (19.5–40.0) |  < 0.001 |
Outcome predictors | Â | Â | Â |
Neurological examination, n | 71 | 447 |  < 0.001 |
 No pupillary and corneal reflex, yes | 0 (0) | 281 (62.9) |  |
NSE, 48 and/or 72 h, n | 56 | 307 |  < 0.001 |
 NSE > 60, yes | 3 (5.4) | 242 (78.8) |  |
SSEP, ≥ 24 h, n | 18 | 132 |  |
 Bilaterally absent N20, yes | 0 (0) | 96 (72.7) |  < 0.001 |
 Time to SSEP, h | 76.0 (67.5–98.0) | 72.0 (60.5–95.5) | 0.731 |
EEG, ≥ 24 h, n | 43 | 206 |  |
 Highly malignant EEG, yes | 0 (0) | 122 (59.2) |  < 0.001 |
 Time to EEG, h | 37.9 (25.2–65.4) | 66.4 (41.8–89.1) | 0.100 |
Brain CT, ≤ 72 h, n | 99 | 503 |  |
 Poor CT, yes | 9 (9.1) | 165 (32.8) |  < 0.001 |
 Time to Brain CT, min | 38.0 (28.0–57.5) | 61.5 (22.5–113.5) | 0.301 |
Brain DWI, 2–7 day, n | 50 | 282 |  |
 Poor DWI, yes | 0 (0) | 220 (78.0) |  < 0.001 |
 Time to Brain DWI, h | 83.0 (76.0–104.5) | 78.0 (68.0–85.0) | 0.145 |