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Fig. 6 | Critical Care

Fig. 6

From: Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Fig. 6Fig. 6

Dose–response relationship between hours of individual PP sessions (day 1) and changes in gas exchange and ultrasonographic indices in PP patients. A Change in ventilatory ratio (VR) at resupination after the first PP session (VR sp0-1) (n = 70). B Change in corrected minute ventilation at resupination after the first PP session (MVcorr sp0-1) (n = 70). C Change in paO2/FiO2 at resupination after the first PP session (paO2/FiO2 sp0-1) (n = 81). D Change in global LUS score (n = 81). E Global LUS reaeration score at day 5 (n = 81). ABG, arterial blood gas analysis; BC, blood chemistry; LUS, lung ultrasound; PP, prone position; pp1: during the first PP session in the PP group; pp2: during the second PP session; SUP: supine position: sp0: supine position timepoint 0 (baseline, after NIV initiation). sp1: supine position timepoint 1 (after the initial 24 h of NIV; in the PP group this also corresponded to the resupination after the first PP session on day 1); sp2: supine position timepoint 2

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