From: Impact of platelet transfusion on outcomes in trauma patients
Early platelet transfusion (n = 766) | No early platelet transfusion (n = 767) | p | |
---|---|---|---|
Age, years | 40 (17) | 41 (19) | 0.07 |
Sex, female | 205 (25%) | 225 (29%) | 0.22 |
Shock Index (prehosp) | 1.6 (0.74) | 1.4 (0.57) | < 0.001 |
SAP, mmHg | 90 (37) | 100 (34) | < 0.001 |
FC, bpm | 103 (34) | 101 (31) | 0.18 |
GCS | 12 [3–15] | 14 [6–15] | < 0.001 |
Base deficit | 12.3 (7.3) | 9.5 (6.4) | < 0.001 |
Haemoglobin (g/dL) | 9.0 (2.5) | 10.0 (2.3) | < 0.001 |
Prothrombin time (%) | 44 (21) | 56 (20) | < 0.001 |
Fibrinogen, g/L | 1.3 (0.8) | 1.6 (0.8) | < 0.001 |
Platelets, G/L | 161 (84) | 202 (82) | < 0.001 |
RBC H6 | 8 [6–13] | 5 [4–6] | < 0.001 |
FFP H6 | 8 [5–11] | 4 [4–5] | < 0.001 |
PCU H6 | 5 [5–10] | 0 [0–0] | < 0.001 |
SAPS 2 | 59 (21) | 51 (22) | < 0.001 |
SOFA | 11 (4) | 9 (4) | < 0.001 |
ISS | 34 [24–48] | 29 [17–41] | < 0.001 |
AIS head | 0 [0–4] | 2 [0–3] | 0.83 |
AIS thorax | 3 [0–4] | 3 [0–4] | 0.001 |
AIS abdomen | 2.5 [0–4] | 2 [0–3] | < 0.001 |
AIS pelvis | 3 [0–4] | 3 [1–4] | 0.47 |
Mortality 24 h | 116 (16%) | 102 (14%) | < 0.001 |
ICU Mortality | 316 (43%) | 231 (31%) | < 0.001 |
Cause of death | |||
Central nervous system | 71 (22%) | 69 (30%) | |
Exsanguination | 107 (34%) | 69 (30%) | < 0.001 |
Multiple organ failure | 94 (30%) | 43 (19%) | |
Withdrawal | 29 (9%) | 22 (9%) | |
Septic shock | 0 (0%) | 6 (3%) | |
Other | 15 (5%) | 22 (9%) |