Table 1 General characteristics of included patients
From: Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients
Patients’ characteristics | n (%) or Med. [IQR] |
|---|---|
Age | 67 [57–74] |
Body mass index (kg/m2) | 22 [20-26] |
Male gender | 21 (70) |
Simplified Acute Physiology Score 2 | 66 [54–79] |
Sequential Organ Failure Assessment | 11 [8–14] |
Comorbidities | |
Diabetes | 7 (23) |
Hypertension | 14 (46) |
Cardiovascular disease | 10 (33) |
Tobacco use | 6 (20) |
Cirrhosis | 3 (10) |
Cancer/hematologic malignancies | 5 (17) |
Septic shock sources | |
Lung | 13 (43) |
Abdomen | 10 (33) |
Urinary tract | 3 (10) |
Catheter | 2 (7) |
Others | 2 (7) |
Organ support therapy | |
Invasive mechanical ventilation | 20 (67) |
Norepinephrine dose (µg/kg/min) | 0.6 [0.3–1.2] |
Crystalloid infusion prior vitamin C (L) | 2.50 [2.10–3.20] |
Hydrocortisone | 12 (40) |
Biological parameters at inclusion | |
Leucocytes (Giga/L) | 11 (1.5–24) |
Hemoglobin (g/dL) | 10.6 (8.3–15.2) |
Platelets (Giga/L) | 132 (50–208) |
Serum creatinine (µmol/L) | 119 (83–182) |
Procalcitonin (ng/mL) | 12 (2.7–30) |
Bicarbonate (mmol/L) | 21 (17–24) |
Arterial lactate (mmol/L) | 3.9 (2.8–5.1) |
Protidemia (g/L) | 57 (46–63) |
Serum albumin (g/L) | 25 (22–31) |
Vitamin C (µmol/L) | 5.3 (2–17) |