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Table 1 General characteristics of included patients

From: Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients

Patients’ characteristics n (%) or Med. [IQR]
Age 67 [57–74]
Body mass index (kg/m2) 22 [20-26]
Male gender 21 (70)
Simplified Acute Physiology Score 2 66 [54–79]
Sequential Organ Failure Assessment 11 [8–14]
Comorbidities
Diabetes 7 (23)
Hypertension 14 (46)
Cardiovascular disease 10 (33)
Tobacco use 6 (20)
Cirrhosis 3 (10)
Cancer/hematologic malignancies 5 (17)
Septic shock sources
Lung 13 (43)
Abdomen 10 (33)
Urinary tract 3 (10)
Catheter 2 (7)
Others 2 (7)
Organ support therapy
Invasive mechanical ventilation 20 (67)
Norepinephrine dose (µg/kg/min) 0.6 [0.3–1.2]
Crystalloid infusion prior vitamin C (L) 2.50 [2.10–3.20]
Hydrocortisone 12 (40)
Biological parameters at inclusion
Leucocytes (Giga/L) 11 (1.5–24)
Hemoglobin (g/dL) 10.6 (8.3–15.2)
Platelets (Giga/L) 132 (50–208)
Serum creatinine (µmol/L) 119 (83–182)
Procalcitonin (ng/mL) 12 (2.7–30)
Bicarbonate (mmol/L) 21 (17–24)
Arterial lactate (mmol/L) 3.9 (2.8–5.1)
Protidemia (g/L) 57 (46–63)
Serum albumin (g/L) 25 (22–31)
Vitamin C (µmol/L) 5.3 (2–17)