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Table 3 Patient characteristics for included studies. Data presented as mean, mean ± SD or median (Q1,Q3)

From: The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis

Study author Age Male (%) Sepsis severity SOFA Infection source (%) Mortality (%)
Chornenki [28] 63.61 ± 15.24 59.9 Sepsis, sepsis + DIC 8.44 ± 2.64 N.R 23.5
Masuda [27] 71.7 ± 58.8 Sepsis, sepsis + DIC N.R N.R 34.57
Ishikura [29] 67.2 ± 17.3 54 Sepsis 7.09 N.R 17.1
Mihajlovic [30] 60.14 ± 16.5 59.3 Sepsis, septic shock 5.73 ± 2.79 N.R 31.3
Dwivedi [31] 63.4 ± 2.24 68.8 Severe sepsis N.R Lungs (52.1), blood (23.9), urinary (2.2), abdomen (10.9), skin (4.3), other (2.2), unknown (4.3) 42.5
Lorente [34] 57 ± 7.3 N.R Severe sepsis, septic shock N.R N.R 52.1
Liaw [33] 63.7 ± 14.91 61.2 Sepsis 8.44 ± 2.82 N.R 23.5
Umemura [32] 72 (63–77) 59.5 Sepsis, sepsis + DIC, septic shock 8 (5–10.5) Lung (14), abdomen (32), urinary tract (29), soft tissue (19), other (6) 16.5
Walborn [35] 57.1 ± 18.6 46.6 Sepsis, sepsis + DIC 5.9 ± 3.7 N.R 14.6
Koyama [36] 69.6 ± 12.9 54.5 Sepsis 9 (7–11) Pulmonary (19.5), abdominal (55.8), urinary tract (6.5), soft tissue (14.3), blood stream (2.6) 19.5
Shapiro [37] 54.9 ± 19.2 47 Sepsis N.R Lower respiratory (31), urogenital (17), soft tissue (12), intra-abdominal (7), catheter-related (5), upper respiratory/suspected viral (14), other (13) 7
Karamarkovic [38] 60.15 N.R Surgical sepsis N.R Abdomen (100) 23
  1. SOFA sequential organ failure assessment scale, N.R not recorded