Table 3 Characteristics and clinical outcomes of matched sample of patients in the Supine vs Prone group
Variable | Supine group, n = 227 | Prone group, n = 227 | Standardized difference |
|---|---|---|---|
Baseline characteristics | |||
Age, years | 53 (40–62) | 51 (40–61) | − 0.08 |
Sex, males | 158 (69.6) | 159 (70.0) | 0.01 |
Obesity (BMI ≥ 30) | 93 (41.0) | 93 (41.0) | 0 |
Chronic respiratory disease | 30 (13.2) | 27 (11.9) | − 0.04 |
Chronic heart failure | 21 (9.3) | 21 (9.3) | 0 |
Chronic liver disease | 6 (2.6) | 8 (3.5) | 0.05 |
Malignancy | 24 (10.6) | 25 (11.0) | 0.01 |
Immunodeficiency | 35 (15.4) | 34 (15.0) | − 0.01 |
Clinical illness severity | |||
SOFA score | 11 (8–14) | 11 (8–14) | 0 |
Baseline PaO2/FiO2, mmHg | 67 (56–77) | 66 (55–80) | − 0.01 |
Before ECMO | |||
Days of mechanical ventilation before ECMO | 4 (1–8) | 3 (1–8) | − 0.03 |
Prone positioning before ECMO | 126 (55.5) | 124 (54.6) | − 0.02 |
Mobile ECMO transfer | 152 (67.0) | 150 (66.1) | − 0.02 |
p-value | |||
Outcome variables | |||
ECMO duration, days | 9 (5–25) | 15 (10–25) | < 0.001 |
ECMO successful weaning | 135 (59.5) | 148 (65.2) | 0.208 |
ICU LOS, days | 24 (12–41) | 31 (19–48) | < 0.001 |
Survivors | 27 (15–49) | 34 (22–49) | 0.024 |
Non-survivors | 19 (7–33) | 23 (15–47) | 0.005 |
Time to successful ECMO weaning within 60 days from ECMO start, days | 56 (8–60) | 24 (12–60) | 0.705 |
ICU mortality | 109 (48.0) | 90 (39.6) | 0.072 |
Hospital mortality | 113/226 (50.0) | 94/226 (41.6) | 0.073 |