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Table 2 Primary and secondary outcomes

From: Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study

Outcomes

Vitamin C (n = 36,327)

Control (n = 36,327)

Difference (95% CI)

p value

Primary outcome

 Hospital mortality, No. (%)

6209 (17.1)

6538 (18.0)

− 0.9 (− 1.3 to − 0.5)a

< 0.001

Secondary outcomes

 90-day mortality, No. (%)

9226 (25.4)

9820 (27.0)

− 3.2 (− 3.8 to − 2.6)

< 0.001

 Vasopressor days, mean (SD)

2.9 (2.3)

[n = 17923]

2.7 (2.0)

[n = 17441]

0.12 (0.1 to 0.2)

0.002

 Ventilator days, mean (SD)

9.5 (18.8)

[n = 10793]

8.2 (15.7)

[n = 10404]

1.4 (1.3 to 1.5)

< 0.001

 Length of stay, mean (SD), days

  ICU

10.6 (17.5)

8.6 (14.2)

2.02 (2.0 to 2.1)

< 0.001

  Hospital

27.1 (41.6)

21.0 (22.1)

6.0 (5.9 to 6.1)

< 0.001

 Hospital costs, mean (SD), U.S. $1000

13.3 (19.0)

12.1 (25.2)

1.19 (1.18 to 1.2)

< 0.001

  1. ICU intensive care unit
  2. aThe mean of all paired differences in the treatment group minus the control group