Table 2 Patient characteristics
From: Predictors for extubation failure in COVID-19 patients using a machine learning approach
Total patients (N = 883) | Successful extubation (N = 707) | Unsuccessful extubation (N = 176) | |
|---|---|---|---|
Male | 71.5% (N = 883) | 70.4% (N = 707) | 75.6% (N = 176) |
Age, years | 63 (55–70, N = 883) | 63 (55–69, N = 707) | 65 (57–72, N = 176) |
Age, years | |||
< 60 | 360 (40.8%) | 301 (42.6%) | 59 (33.5%) |
60–70 | 314 (35.6%) | 249 (35.2%) | 65 (36.9%) |
70–80 | 199 (22.5%) | 150 (21.2%) | 49 (27.8%) |
> 80 | 10 (1.1%) | 7 (1.0%) | 3 (1.7%) |
Body mass index, kg/m2 | 27.9 (25.1–31.6, N = 809) | 28.4 (25.4–32.0, N = 642) | 26.8 (24.2–30.1, N = 167) |
Body mass index, kg/m2 | |||
< 25 | 200 (24.7%) | 145 (22.6%) | 55 (32.9%) |
25–30 | 336 (41.5%) | 267 (41.6%) | 69 (41.3%) |
30–35 | 174 (21.5%) | 145 (22.6%) | 29 (17.4%) |
> 35 | 98 (12.1%) | 84 (13.1%) | 14 (8.4%) |
Lab values (last 24 h before extubation) | |||
C-reactive protein, mg/L | 57 (23–114, N = 731) | 53 (21–108, N = 583) | 72 (33–146, N = 148) |
Creatinine, micromol/L | 66 (52–96, N = 820) | 65 (52–90, N = 657) | 66 (53–108, N = 163) |
Leukocyte count, 109/L | 11.3 (8.8–14.2, N = 817) | 11.2 (8.8–13.9, N = 653) | 11.7 (8.9–15.5, N = 164) |
Thrombocyte count, 109/L | 350 (269–457, N = 824) | 356 (269–462, N = 664) | 340 (259–419, N = 160) |
Respiratory characteristics (last measured) | |||
Time since last controlled mode, hours | 74 (35–130, N = 773) | 77 (37–137, N = 603) | 64 (27–115, N = 170) |
FiO2, % | 36 (30–41, N = 866) | 35 (30–41, N = 691) | 40 (33–45, N = 175) |
Pressure above PEEP, cmH2O | 6 (5–9, N = 773) | 6 (5–10, N = 617) | 7 (5–8, N = 156) |
PEEP, cmH2O | 8 (5–8, N = 867) | 8 (6–9, N = 693) | 7 (5–8, N = 174) |
Respiratory rate, /min | 22 (18–26, N = 883) | 22 (18–26, N = 707) | 23 (18–27, N = 176) |
Tidal volume, ml/kg IBW | 7.5 (6.4–9.0, N = 857) | 7.5 (6.3–8.9, N = 682) | 7.6 (6.6–9.1, N = 175) |
Ventilatory ratio | 1.8 (1.4–2.3, N = 722) | 1.8 (1.4–2.3, N = 577) | 1.9 (1.5–2.4, N = 145) |
P/F ratio | 206 (168–258, N = 861) | 209 (171–262, N = 690) | 192 (163–242, N = 171) |
pO2 arterial, mmHg | 74 (67–84, N = 792) | 75 (68–85, N = 634) | 72 (65–83, N = 158) |
pCO2 arterial, mmHg | 41 (37–46, N = 732) | 41 (37–46, N = 579) | 40 (36–46, N = 153) |
Bicarbonate arterial, mmol/L | 29 (26–31, N = 861) | 29 (26–32, N = 688) | 28 (25–31, N = 173) |
Airway occlusion pressure (P0.1), cmH2O | 2.1 (1.3–3.8, N = 450) | 2.1 (1.2–3.7, N = 356) | 2.3 (1.4–4.0, N = 94) |