Characteristic | Patients (n = 436) | Controls (n = 50) | p |
---|---|---|---|
Demographics at 5-year follow-up | |||
Male sex, no (%) | 302 (69.3) | 35 (70.0) | 0.91 |
Age (years), median (IQR) | 61 (51–69) | 61 (57–66) | 0.51 |
BMI (kg/m2), median (IQR) | 27.3 (24.2–30.5) | 26.4 (23.7–29.3) | 0.30 |
Physical function at 5-year follow-up | |||
Univariable analysis | |||
Handgrip strength dominant hand (%pred), median (IQR) | 93 (78–107) | 104 (91–119) | < 0.0001 |
Handgrip strength non-dominant hand (%pred), median (IQR) | 100 (83–117) | 114 (102–125) | 0.0002 |
6-min walk distance (%pred), median (IQR) | 95 (80–106) | 117 (107–125) | < 0.0001 |
Physical component score SF36, median (IQR) | 48 (38–55) | 55 (51–58) | < 0.0001 |
Multivariable analysisa | |||
Handgrip strength dominant hand (%pred), β-estimate (95% CI) | − 6.194 (− 9.369; − 3.019) | 0.0001 | |
Handgrip strength non-dominant hand (%pred), β-estimate (95% CI) | − 5.401 (− 8.962; − 1.840) | 0.0030 | |
6-min walk distance (%pred), β-estimate (95% CI) | − 11.151 (− 14.212; − 8.091) | < 0.0001 | |
Physical component score SF36, β-estimate (95% CI) | − 3.781 (− 5.326; − 2.235) | < 0.0001 |