Table 1 Characteristics and outcomes of enrolled children by mechanical power quartiles
From: Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study
|  | Mechanical power quartiles (J·min−1·Kg−1 predicted body weight) | |||
|---|---|---|---|---|
 < 0.29 | 0.29–0.41 | 0.41–0.62 |  ≥ 0.62 | |
n | 76 | 77 | 76 | 77 |
Patient characteristics | ||||
Age (years)a | 6.0 (1.4, 14.4) | 2.3 (0.4, 8.2) | 1.6 (0.4, 9) | 0.9 (0.3, 4) |
Male | 47 (61.8%) | 50 (64.9%) | 52 (68.4%) | 43 (55.8%) |
Central/South America | 7 (8.3%) | 10 (11.9%) | 8 (9.4%) | 14 (17.3%) |
Europe | 14 (16.7%) | 14 (16.7%) | 5 (5.9%) | 6 (7.4%) |
Asia/Australia | 4 (4.8%) | 6 (7.1%) | 4 (4.7%) | 5 (6.2%) |
North America | 59 (70.2%) | 54 (64.3%) | 68 (80%) | 56 (69.1%) |
Comorbid condition | 49 (58.3%) | 48 (57.1%) | 44 (51.8%) | 52 (64.2%) |
Bronchopulmonary Dysplasia | 1 (1.2%) | 1 (1.2%) | 4 (4.7%) | 13 (16.1%) |
PARDS characteristics | ||||
Direct Lung Injury | 60 (70.6%) | 54 (63.5%) | 58 (66.7%) | 64 (76.2%) |
Oxygenation Indexb | 4.9 (3.7, 7.7) | 7.6 (5.0, 12.1) | 8.6 (5.3, 13.7) | 11.1 (6.8, 16.1) |
NIV at Diagnosis | 5 (6.6%) | 8 (10.4%) | 7 (9.2%) | 9 (11.7%) |
Ventilator management parameters | ||||
Mechanical ventilation mode pressure controlled | 18 (23.7%) | 29 (37.7%) | 29 (38.2%) | 45 (58.4%) |
PRVC | 22 (29%) | 20 (26%) | 30 (39.5%) | 21 (27.3%) |
Volume controlled | 24 (31.6%) | 21 (27.3%) | 8 (10.5%) | 0 (0%) |
Multiple modes | 12 (15.8%) | 7 (9.1%) | 9 (11.8%) | 11 (14.3%) |
VT (ml/kg predicted body weight) | 6.7 (5.6, 7.6) | 7.2 (5.8, 8.6) | 7.7 (7, 8.9) | 8.8 (7.4, 10) |
PIP (cm H2O) | 22 (19, 24) | 26 (23, 29) | 28 (25, 32) | 32 (30, 36) |
Delta pressure (cm H2O) | 14 (12, 18) | 18 (14, 20) | 20 (17, 22) | 23 (20, 27) |
RR (bpm) | 19 (15, 24) | 22 (18, 28) | 24 (20, 30) | 30 (25, 35) |
PEEP (cm H2O) | 7 (6, 8) | 8 (6, 10) | 8 (7, 10) | 8 (7, 11) |
pCO2c | 42 (37, 50) | 45 (38, 54) | 48 (40, 55) | 54 (43, 61) |
pHc | 7.36 (7.30, 7.42) | 7.35 (7.30, 7.40) | 7.31 (7.25, 7.39) | 7.33 (7.25, 7.38) |
Outcomes | ||||
28-day VFD (IMV) | 21.4 (13.6, 24.7) | 21.7 (15.0, 24.2) | 18.1 (4.7, 21.9) | 15.6 (0, 21.6) |
28-day VFD (IMV and NIV) | 21.2 (8.7, 24.4) | 20.8 (12.4, 23.5) | 17.4 (0.3, 21.9) | 14.8 (0, 21.0) |
Length of ventilation (survivors) | 5.3 (3.0, 12.5) | 5.9 (3.7, 10.4) | 8.2 (4.2, 14.1) | 9.3 (5.2, 13.9) |
ICU mortality | 7 (9.2%) | 8 (10.4%) | 12 (15.8%) | 22 (28.6%) |