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Fig. 3 | Critical Care

Fig. 3

From: Lung histopathologic clusters in severe COVID-19: a link between clinical picture and tissue damage

Fig. 3

Heatmap of histopathologic patterns of the studied subjects. Patients on the right (n = 27) had no full clinical data: 18 came from other hospitals, three came directly from home, and six were emergency department patients. They differed from patients on the left in the extension of early proliferative DAD, AFOP, interstitial pneumonia, late proliferative DAD, bronchopneumonia, thrombi, megakaryocytes, and normal lung areas (see Additional file 1: Table S2). Only nine patients in the group on the right were admitted to ICU; the remaining died in medical wards or ED. Although in the group on the right clinical data are missing, the exposure to PPV and PEEP is presumptively different from the patients considered in the analysis (group on the left) on which 43 out of 48 subjects underwent to mechanical ventilation. The column on the right shows the histopathologic score (see methods in the text)

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