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Fig. 4 | Critical Care

Fig. 4

From: 17α-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a randomized control trial

Fig. 4

Box-and-scatter plots depicting all primary and significant secondary variables from point-of-care (POC; Panel A), invasive hemodynamic (Hemo; Panel B), and blood protein (Panel C) markers for survival analyses. All data were obtained from the last available, non-terminal timepoint for the non-surviving cohort, and the equivalent time point for each animal’s match (Surviving cohort). Graphed data have been residualized (Rsd.) to account for the effects of initial baseline values and varying measurement acquisition time post-injury. In the case of larger adjustments, this means that negative values are possible. Plots for primary POC measurements (glucose, lactate, bicarbonate [HCO3]), significant secondary POC measurements (potassium [K], potential hydrogen [pH]), primary hemodynamic measurements (shock-index [SI] and pulse-pressure [PP]), primary blood protein markers (neurofilament light chain [NFL], ubiquitin C-terminal hydrolase [UCH-L1], glial fibrillary acidic protein [GFAP]) and significant secondary protein markers (amyloid-beta 42 [Aβ42]) are displayed. Asterisks denote significant main effects of Survival Status

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Critical Care

ISSN: 1364-8535