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Table 4 Predictive value of “highly malignant” and “malignant” electroencephalography patterns and dominant electroencephalography frequency for poor neurologic outcome at 1 month

From: Background frequency can enhance the prognostication power of EEG patterns categories in comatose cardiac arrest survivors: a prospective, multicenter, observational cohort study

Variables

EEG timing

True positive

False positive

True negative

False negative

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

Accuracy (95% CI)

Highly malignant pattern

 < 72 h

144

0

110

99

59.3 (52.8–65.5)

100.0 (96.7–100.0)

100

52.6 (48.8–56.4)

72.0 (67.0–76.6)

Between 72 h and 7 days

55

0

38

43

56.1 (45.7–66.1)

100.0 (90.8–100.0)

100

46.9 (41.4–52.5)

68.4 (59.9–76.1)

 < 7 days

199

0

148

142

58.4 (52.9–63.6)

100.0 (97.5–100.0)

100

51.0 (47.9–54.2)

71.0 (66.7–75.0)

Highly malignant or malignant patterns

 < 72 h

208

24

86

35

85.6 (80.5–89.8)

78.2 (69.3–85.5)

89.7 (85.8–92.5)

71.1 (64.0–77.2)

83.3 (79.0–87.0)

Between 72 h and 7 days

81

17

28

10

82.7 (73.7–89.6)

73.7 (56.9–86.6)

89.0 (82.5–93.3)

62.2 (50.7–72.5)

80.2 (72.5–86.5)

 < 7 days

289

34

114

52

84.8 (80.5–88.4)

77.0 (69.4–83.5)

89.5 (86.3–92.0)

68.7 (62.7–74.1)

82.4 (78.7–85.7)

Highly malignant or malignant patterns with delta or undetermined frequency

 < 72 h

171

2

108

72

70.4 (64.2–76.0)

98.2 (93.6–99.8)

98.8 (95.6–99.7)

60.0 (55.2–64.6)

79.0 (74.4–83.2)

Between 72 h and 7 days

65

1

37

33

66.3 (56.1–75.6)

97.4 (86.2–99.9)

98.5 (90.3–99.8)

52.9 (45.8–59.8)

75.7 (67.9–82.0)

< 7 days

236

3

145

105

69.2 (64.0–74.1)

98.0 (94.2–99.6)

98.7 (96.2–99.6)

58.0 (54.0–61.9)

77.9 (74.0–81.5)

  1. CI, confidence interval; EEG, electroencephalography; NPV, negative predictive value; PPV, positive predictive value