Skip to main content

Table 4 Predictive value of “highly malignant” and “malignant” electroencephalography patterns and dominant electroencephalography frequency for poor neurologic outcome at 1 month

From: Background frequency can enhance the prognostication power of EEG patterns categories in comatose cardiac arrest survivors: a prospective, multicenter, observational cohort study

Variables EEG timing True positive False positive True negative False negative Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) Accuracy (95% CI)
Highly malignant pattern  < 72 h 144 0 110 99 59.3 (52.8–65.5) 100.0 (96.7–100.0) 100 52.6 (48.8–56.4) 72.0 (67.0–76.6)
Between 72 h and 7 days 55 0 38 43 56.1 (45.7–66.1) 100.0 (90.8–100.0) 100 46.9 (41.4–52.5) 68.4 (59.9–76.1)
 < 7 days 199 0 148 142 58.4 (52.9–63.6) 100.0 (97.5–100.0) 100 51.0 (47.9–54.2) 71.0 (66.7–75.0)
Highly malignant or malignant patterns  < 72 h 208 24 86 35 85.6 (80.5–89.8) 78.2 (69.3–85.5) 89.7 (85.8–92.5) 71.1 (64.0–77.2) 83.3 (79.0–87.0)
Between 72 h and 7 days 81 17 28 10 82.7 (73.7–89.6) 73.7 (56.9–86.6) 89.0 (82.5–93.3) 62.2 (50.7–72.5) 80.2 (72.5–86.5)
 < 7 days 289 34 114 52 84.8 (80.5–88.4) 77.0 (69.4–83.5) 89.5 (86.3–92.0) 68.7 (62.7–74.1) 82.4 (78.7–85.7)
Highly malignant or malignant patterns with delta or undetermined frequency  < 72 h 171 2 108 72 70.4 (64.2–76.0) 98.2 (93.6–99.8) 98.8 (95.6–99.7) 60.0 (55.2–64.6) 79.0 (74.4–83.2)
Between 72 h and 7 days 65 1 37 33 66.3 (56.1–75.6) 97.4 (86.2–99.9) 98.5 (90.3–99.8) 52.9 (45.8–59.8) 75.7 (67.9–82.0)
< 7 days 236 3 145 105 69.2 (64.0–74.1) 98.0 (94.2–99.6) 98.7 (96.2–99.6) 58.0 (54.0–61.9) 77.9 (74.0–81.5)
  1. CI, confidence interval; EEG, electroencephalography; NPV, negative predictive value; PPV, positive predictive value