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Table 1 Demographic and clinical characteristics of the study patients according to electroencephalography timing

From: Background frequency can enhance the prognostication power of EEG patterns categories in comatose cardiac arrest survivors: a prospective, multicenter, observational cohort study

Characteristics Total (N = 489) Patients with EEG < 72 h
(N = 353)
Patients with EEG of 72 h to 7 days (N = 136) P value
Age, years 58.0 (46.0–69.0) 58.0 (46.0–69.0) 57.0 (46.3–67.0) 0.515
Male 341 (69.7%) 251 (71.1%) 90 (66.2%) 0.288
Previous medical history     
 Hypertension 171 (35.0%) 127 (36.0%) 44 (32.4%) 0.451
 Diabetes mellitus 99 (20.2%) 78 (22.1%) 21 (15.4%) 0.101
 Acute myocardial infarction 25 (5.1%) 16 (4.5%) 9 (6.6%) 0.348
 Congestive heart failure 18 (3.7%) 13 (3.7%) 5 (3.7%) 0.997
 Chronic kidney disease 38 (7.8%) 30 (8.5%) 8 (5.9%) 0.333
Cardiac arrest characteristics     
 Witnessed 313 (64.0%) 228 (64.6%) 85 (62.5%) 0.666
 Bystander CPR 296 (60.5%) 212 (60.1%) 84 (61.8%) 0.729
 Initial shockable rhythm 169 (34.6%) 127 (36.0%) 42 (30.9%) 0.288
 No flow time, min 1.0 (0.0–6.0) 1.0 (0.0–6.0) 1.0 (0.0–7.0) 0.935
 Resuscitation duration, min 24.0 (13.5–36.0) 24.0 (13.0–37.5) 24.0 (14.0–32.0) 0.48
Time from ROSC to TTM initiation, hours 3.2 (2.0–4.7) 3.2 (1.9–4.6) 3.3 (2.2–4.7) 0.599
Target temperature     0.049
 33 °C 273 (55.8%) 185 (52.4%) 88 (64.7%)  
 34–35 °C 160 (32.7%) 124 (35.1%) 36 (26.5%)  
 36 °C 56 (11.5%) 44 (12.5%) 12 (8.8%)  
Time from ROSC to EEG examination, hours 46.6 (23.9–73.9) 31.5 (20.0–52.0) 90.8 (77.8–106.1)  < 0.001
Poor neurological outcome at 1 month 341 (69.7%) 243 (68.8%) 98 (72.1%) 0.487
Death at 1 month 231 (47.2%) 166 (47.0%) 65 (47.8%) 0.879
Poor neurological outcome at 6 months 335 (69.4%),
N = 483
237 (68.3%),
N = 347
98 (72.1%),
N = 136
0.420
Death at 6 months 276 (57.1%),
N = 483
197 (56.8%),
N = 347
79 (58.1%),
N = 136
0.793
  1. Values are expressed as median (interquartile range) or n (%) as appropriate
  2. CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation; TTM, targeted temperature management; EEG, electroencephalography