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Table 2 Main characteristics of severe COVID-19 patients classified according to respiratory support at inclusion

From: Peripheral microcirculatory alterations are associated with the severity of acute respiratory distress syndrome in COVID-19 patients admitted to intermediate respiratory and intensive care units

 

Invasive mechanical ventilation

(n = 39)

Non-invasive respiratory support

(n = 34)

Age (years)

59 ± 12

59 ± 14

Gender (male), n (%)

28 (72)

23 (68)

BMI

30 ± 5

30 ± 6

Days from hospitalization (n)

5 ± 4

5 ± 4

Days from IRCU/ICU admission (n)

4 ± 3

3 ± 3

Pre-existing comorbidities (n, %)

  

Hypertension

18 (46)

15 (44)

Diabetes mellitus

8 (21)

9 (26)

Smoker

7 (18)

11 (32)

COPD

2 (5)

5 (15)

Respiratory support (n, %)

  

Mechanical ventilation

39 (100%)

HFNC

23 (68%)

NIV

3 (9%)

Venturi mask

8 (23%)

Sedative agents (n, %)

39 (100)

0

NMBA (n, %)

17 (44)

0

Vasopressor support (n, %)

12 (29)

0

Temperature (°C)

36.2 ± 0.9

36.3 ± 0.5

HR (beats/min)

74 ± 15

82 ± 16*

MAP (mmHg)

83 ± 10

89 ± 13*

RR (resp/min)

22 ± 4

21 ± 6

FiO2 (%)

53 ± 21

56 ± 20

PaO2 (mmHg)

82 ± 14

PaCO2 (mmHg)

45 ± 8

pH

7.38 ± 0.07

SpO2 (%)

96 ± 2

93 ± 5*

PF ratio

174 ± 54

SF ratio

204 ± 64

200 ± 98

Hb (g/dL)

12.4 ± 2.0

13.7 ± 1.8*

D-Dimer (ng/mL)

5528 ± 8833

7499 ± 20,109

Ferritin (ng/mL)

1786 ± 918

1201 ± 993*

StO2 (%)

67 ± 6

67 ± 6

THC (μM/L)

41 ± 13

44 ± 18

DeO2 (%/min)

 − 4.9 ± 1.8

 − 5.6 ± 2.1

ReO2 (%/min)

72 ± 36

83 ± 38

Hyperemia AUC (U)

8.2 ± 5.2

8.8 ± 4.8

  1. BMI, body mass index; IRCU, Intermediate Respiratory Care Unit; ICU, Intensive Care Unit; COPD, chronic obstructive pulmonary disease; HFNC, high-flow nasal cannula; NIV, non-invasive ventilation; NMBA, neuromuscular blocking agents; HR, heart rate; MAP, mean arterial pressure; RR, respiratory rate; FiO2, fraction of inspired oxygen; PaO2, arterial partial pressure of oxygen; PaCO2, arterial partial pressure of carbon dioxide; SpO2, pulse-oximetric oxygen saturation; PF ratio, PaO2 to FiO2 ratio; SF ratio, SpO2 to FiO2 ratio; Hb, hemoglobin; StO2, tissue oxygen saturation; THC, tissue hemoglobin concentration; DeO2, deoxygenation rate; ReO2, reoxygenation rate; AUC, area under the curve
  2. *p < 0.05