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Table 1 Main characteristics of the studied healthy volunteers and critically ill COVID-19 patients at inclusion

From: Peripheral microcirculatory alterations are associated with the severity of acute respiratory distress syndrome in COVID-19 patients admitted to intermediate respiratory and intensive care units

  Healthy volunteers (n = 32) COVID-19 patients
(n = 73)
Age (years) 34 ± 10 59 ± 13*
Gender (male), n (%) 16 (50) 51 (70)*
BMI 23 ± 3 30 ± 5*
Days from hospitalization (n) 5 ± 4
Days from IRCU/ICU admission (n) 3 ± 3
APACHE II score 14 ± 8
Pre-existing comorbidities (n, %)   
Hypertension 33 (45)
Diabetes mellitus 17 (23)
Smoker 18 (25)
COPD 7 (10)
Temperature (°C) 36.3 ± 0.3 36.0 ± 0.7
HR (beats/min) 75 ± 13 77 ± 16
MAP (mmHg) 83 ± 9 86 ± 12
RR (resp/min) 18 ± 3 22 ± 5*
SpO2 (%) 97 ± 2 95 ± 4
FiO2 (%) 21 ± 0 54 ± 21*
StO2 (%) 65 ± 3 67 ± 6
THC (μM/L) 45 ± 11 43 ± 16
DeO2 (%/min) − 9.1 ± 2.4 − 5.2 ± 2.0*
ReO2 (%/min) 120 ± 55 77 ± 37*
Hyperemia AUC (U) 14.8 ± 6.8 8.5 ± 5.0*
  1. BMI, body mass index; IRCU, Intermediate Respiratory Care Unit; ICU, Intensive Care Unit; COPD, chronic obstructive pulmonary disease; HR, heart rate; MAP, mean arterial pressure; RR, respiratory rate; SpO2, pulse-oximetric oxygen saturation; FiO2, fraction of inspired oxygen; StO2, tissue oxygen saturation; THC, tissue hemoglobin concentration; DeO2, deoxygenation rate; ReO2, reoxygenation rate; AUC, area under the curve
  2. *p < 0.05