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Table 3 Costs of health care use per patient for PCT-guided decision making and standard care (2015€)

From: Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

 

PCT-guided decision making (n = 754)

Standard care (n = 735)

 

All countries

The Netherlands

Switzerland

Canada

Czech Republic

P valuea

All countries

The Netherlands

Switzerland

Canada

Czech Republic

P valuea

All patients

3649 [1496, 4091]

2750 [1315, 3304]

5813 [3073, 7415]

4823 [2271, 5062]

2328 [1360, 3160]*

< 0.001*

3616 [1639, 4372]

2710 [1456, 3272]

6091 [3579, 6965]

4844

[2366, 5867]

1242 [780, 1618]*

< 0.001*

Per risk category

            

Infection possible (medium risk)

4247 [1989, 4833]

3375 [1667, 3726]

6324 [3376, 7957]

4511 [2221, 4850]

2294 [1240, 3337]*

< 0.001*

4238 [2023, 5021]

3260 [1863, 3467]

6474 [3350, 7947]

4867 [2298, 6343]

1279 [812, 1768]*

< 0.001*

Infection unlikely (low risk)

2960 [1295, 3389]*

2255 [1210, 3062]*

3977 [2404, 5346]*

5218 [2277, 5526]

2415 [1730, 3160]*

< 0.001*

2962 [1424, 3591]*

2267 [1316, 3166]*

4958 [3781, 6314]*

4818 [2495, 5046]

1195 [628, 1559]*

< 0.001*

P valuea

< 0.001*

< 0.001*

0.004*

0.864

0.508

 

< 0.001*

< 0.001*

0.322

0.697

0.456

 

Per gestational age (GA)

GA < 37 weeks

6436 [2853, 8728]

5609 [2638, 8653]

9760 [6407, 11596]

5466 [2302, 5610]

2978 [1500, 4267]*

< 0.001*

6098 [2881, 7945]

5354 [2779, 7349]

9045 [4858, 11572]

4867 [2648, 6580]

884

[605, 1263]*

< 0.001*

GA ≥ 37 weeks

2928 [1376, 3468]

2234 [1276, 3150]*

4069 [2615, 4794]*

4585 [2173, 4989]

2133 [1174, 2913]*

< 0.001*

2986 [1538, 3494]

2245 [1416, 3141]*

4427 [3253, 5127]*

4836 [2315, 5681]

1304 [812, 1768]*

< 0.001*

P valuea

< 0.001*

< 0.001*

< 0.001*

0.454

0.269

 

< 0.001*

< 0.001*

< 0.001*

0.524

0.216

 
  1. Data are expressed as mean + IQR (interquartile range)
  2. Costs are expressed in € corrected for inflation for the year 2015
  3. *Significant at a 5% level (P < 0.05)
  4. aP value for comparison between the subgroups (country, risk category or gestational age)
  5. If costs are ended with *, this indicates statistically significant difference between the PCT-guided decision-making group and standard care group
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Critical Care

ISSN: 1364-8535