Skip to main content

Table 3 COVID-19 Inflammatory surrogate markers: peak levels follow-up

From: Evaluation of zinc sulfate as an adjunctive therapy in COVID-19 critically ill patients: a two center propensity-score matched study

 

Surrogate markers*

P-value^

Beta coefficient (estimates) (95%CI)

P-value$*

Control

Zinc

Ferritin level (ug/l), Median (Q1, Q3)§

891.9 (350.0, 2476.0)

941.1 (511.0, 2344.0)

0.69

0.21 (− 0.18, 0.60)

0.29

D-dimer level (mg/l), Mean (SD)§

15.0 (36.8)

6.7 (9.2)

0.75

− 0.80 (− 1.28, − 0.32)

0.001

Fibrinogen Level (gm/l), Median (Q1, Q3)§

5.5 (3.39, 7.18)

4.8 (3.95, 6.65)

0.31

− 0.99 (− 1.51, − 0.48)

0.0002

C-reactive protein (mg/l), Mean (SD)§

184.2 (148.1)

174.0 (124.3)

0.92

− 0.05 (− 0.36, 0.27)

0.77

  1. §Denominator is the total number of patients
  2. ^Wilcoxon rank sum test is used to calculate the P-value
  3. $*Generalized linear model is used to calculate estimates and p-value
  4. *All levels represent peak levels for each one of the biomarkers