Skip to main content

Table 2 Outcome of 1491 patients not intubated on the day of intensive care unit (ICU) admission, according to oxygenation strategy

From: Benefits and risks of noninvasive oxygenation strategy in COVID-19: a multicenter, prospective cohort study (COVID-ICU) in 137 hospitals

 

No

All patients

Standard oxygen

HFNC

NIV

P value

(n = 1491)

(n = 766)

(n = 567)

(n = 158)

 

Invasive mechanical ventilation, n (%)

1491

678 (45)

359 (47)

242 (43)

77 (49)

0.217

Time between ICU admission and invasive mechanical ventilation, days

635

2 (1–3)

2 (1–2)

2 (1–3)

2 (1–3)

0.012

ICU mortality without being intubated, n (%)

1491

61 (4)

13 (2)

30 (5)

18 (11)

 < 0.001

Oxygenation failure rate, n (%)

1491

739 (50)

372 (49)

272 (48)

95 (60)

 < 0.001

ICU mortality, n (%)

1487

269 (18)

108 (14)

109 (19)

52 (33)

 < 0.001

ICU length of stay, days

1477

8 (3–18)

7 (3–16)

9 (5–18)

9 (4–20)

 < 0.001

Hospital mortality, n (%)

1439

307 (21)

127 (17)

118 (22)

62 (40)

 < 0.001

Hospital length of stay, days

1400

17 (11–28)

16 (10–27)

18 (12–29)

16 (11–27)

0.0039

Day 28 mortality, n (%)

1491

276 (19)

115 (15)

106 (19)

55 (35)

 < 0.001

Day 60 mortality, n (%)

1491

308 (21)

130 (17)

117 (21)

61 (39)

 < 0.001

Day 90 mortality, n (%)

1491

311 (21)

130 (17)

118 (21)

63 (40)

 < 0.001

  1. Results are expressed as n (%) or median (25th–75th percentiles)
  2. HFNC high-flow nasal cannula, NIV noninvasive ventilation, ICU intensive care unit