Baseline parameters | Standard-MAP N = 6 | High-MAP N = 6 | p |
---|---|---|---|
Systemic hemodynamic | |||
Heart rate (bpm) | 78 ± 5 | 82 ± 9 | 0.55 |
MAP (mmHg) | 95 ± 16 | 98 ± 14 | 0.54 |
Cerebral hemodynamic | |||
Intracranial pressure (cm H2O) | 10 ± 1 | 10 ± 1 | 0.84 |
Cerebral perfusion pressure (mmHg) | 84 ± 7 | 87 ± 6 | 0.73 |
Carotid blood flow (ml/min) | 156 ± 27 | 137 ± 8 | 0.52 |
Cerebral oxygen consumption (ml O2/min/kg) | 45 ± 3 | 48 ± 7 | 0.63 |
NIRS cerebral oxygen saturation (%) | 62 ± 5 | 56 ± 2 | 0.68 |
Blood biochemistry | |||
pH | 7.46 ± 0.02 | 7.42 ± 0.01 | 0.21 |
PaO2 (mmHg) | 158 ± 3 | 152 ± 7 | 0.68 |
PaCO2 (mmHg) | 37 ± 2 | 40 ± 2 | 0.22 |
HCO3− (mmol/L) | 25 ± 1 | 25 ± 2 | 0.88 |
Lactate (mmol/L) | 2.5 ± 0.5 | 4.4 ± 1.4 | 0.34 |
Hemoglobin (g/dL) | 9.2 ± 0.4 | 9.6 ± 0.4 | 0.52 |