Skip to main content

Table 2 Summary of the outcomes of different subgroups

From: Predictive power of extubation failure diagnosed by cough strength: a systematic review and meta-analysis

  Measurement of cough peak flow Measurement of semiquantitative cough strength score
Voluntary CPF Involuntary CPF CPF measured with an external flowmeter CPF measured with a ventilator SCSS (grade 0 to 4/5) WCT Other#
No. of study arms 17 6 18 5 8 4 10
Total cases 2282 529 2023 718 1342 406 3918
Total tests 2408 610 2300 718 1342 406 3918
Pooled sensitivity 0.73 (0.68–0.78) 0.82 (0.73–0.88) 0.77 (0.72–0.81) 0.72 (0.60–0.81) 0.36 (0.26–0.48) 0.70 (0.44–0.88) 0.59 (0.41–0.47)
Pooled specificity 0.72 (0.65–0.79) 0.82 (0.74–0.88) 0.74 (0.67–0.81) 0.77 (0.69–0.84) 0.87 (0.80–0.91) 0.74 (0.61–0.84) 0.83 (0.62–0.64)
Pooled positive LR 2.7 (2.1–3.4) 4.5 (2.9–7.0) 3.0 (2.3–4.0) 3.1 (2.1–4.6) 2.7 (2.1–3.6) 2.7 (1.5–4.8) 3.5 (1.5–8.2)
Pooled negative LR 0.37 (0.31–0.45) 0.22 (0.14–0.35) 0.31 (0.25–0.39) 0.37 (0.25–0.55) 0.73 (0.64–0.84) 0.40 (0.18–0.90) 0.49 (0.33–0.73)
Pooled DOR 7 (5–10) 21 (9–48) 10 (6–15) 9 (4–18) 4 (3–5) 7 (2–25) 7 (2–21)
Pooled AUC 0.76 (0.72–0.79) 0.89 (0.86–0.91) 0.80 (0.77–0.84) 0.77 (0.73–0.81) 0.70 (0.65–0.73) 0.78 (0.74–0.82) 0.75 (0.71–0.79)
  1. CPF = cough peak flow, SCSS = semiquantitative cough strength score, WCT = white card test, LR = likelihood ratio, DOR = diagnostic odds ratio, AUC = area under the receiver operating characteristic curve
  2. #Includes strong, moderate, and weak; strong, weak, and no cough; effective and ineffective; with or without spontaneous cough; excellent, moderate, and poor; strong and weak; strong and not strong; and effective, moderate, and ineffective