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Table 1 Baseline characteristics in the control and treated groups

From: Effectiveness of anisodamine for the treatment of critically ill patients with septic shock: a multicentre randomized controlled trial

Variables

Total (n = 355)

Control (n = 174)

Treated (n = 181)

Age (years), Median (Q1, Q3)

68 (57, 79)

67 (56, 78)

69 (58.75, 79)

Gender, male n (%)

217 (61)

104 (60)

113 (62)

Source of admission, n (%)

   

 Emergency room

108 (30)

52 (30)

56 (31)

 Other

10 (3)

2 (2)

8 (5)

 Postoperative

114 (32)

57 (33)

57 (31)

 Transfer from other hospital

2 (1)

2 (1)

0 (0)

 Ward

121 (34)

61 (35)

60 (33)

Type, n (%)

   

 Emergency operation

109 (31)

57 (33)

52 (29)

 Medical

194 (55)

91 (52)

103 (57)

 Optional operation

52 (15)

26 (15)

26 (14)

Comorbidity

   

 Diabetes, n (%)

74 (21)

40 (23)

34 (19)

 Hypertension, n (%)

92 (26)

46 (26)

46 (26)

 Myocardial infarction, n (%)

14 (4)

8 (5)

6 (3)

 Heart failure, n (%)

22 (6)

11 (6)

11 (6)

 Cerebrovascular, n (%)

29 (8)

17 (10)

12 (7)

 Dementia, n (%)

11 (3)

6 (3)

5 (3)

 COPD, n (%)

23 (6)

10 (6)

13 (7)

 Connective tissue, n (%)

18 (5)

9 (5)

9 (5)

 Paralysis, n (%)

7 (2)

4 (2)

3 (2)

 Renal failure, n (%)

13 (4)

7 (4)

6 (3)

 Malignancy, n (%)

59 (17)

33 (19)

26 (14)

 Hematological malignancy, n (%)

8 (2)

4 (2)

4 (2)

 Cirrhosis, n (%)

11 (3)

3 (2)

8 (4)

 Metastatic tumor, n (%)

15 (4)

8 (5)

7 (4)

 Immunosuppression, n (%)

28 (8)

17 (10)

11 (6)

Infection sites, n (%)

   

 Abdominal

114 (32)

61 (35)

53 (29)

 Bile duct

24 (7)

6 (3)

18 (10)

 Bloodstream

21 (6)

9 (5)

12 (7)

 CNS

2 (1)

2 (1)

0 (0)

 Gastrointestine

9 (3)

5 (3)

4 (2)

 Hemo

4 (1)

3 (2)

1 (1)

 Liver abscess

3 (1)

1 (1)

2 (1)

 Mediastinum

1 (0)

0 (0)

1 (1)

 Lower respiratory tract

116 (33)

63 (36)

53 (29)

 Skin

10 (3)

6 (3)

4 (2)

 Thoracic

3 (1)

1 (1)

2 (1)

 Unknown

14 (4)

5 (3)

9 (5)

 Urinary tract

34 (10)

12 (7)

22 (12)

SOFA, median (Q1, Q3)

8 (5, 11)

8 (6, 11)

8 (5, 10)

GCS, median (Q1, Q3)

14 (11, 15)

14 (11, 15)

15 (11, 15)

MV, n (%)

177 (51)

94 (54)

83 (47)

CRRT, n (%)

26 (7)

14 (8)

12 (7)

  1. MV mechanical ventilation, CRRT continuous renal replacement therapy, GCS Glasgow coma scale, SOFA sequential organ failure assessment, CNS central nervous system, COPD chronic obstructive pulmonary disease, Q1 first quartile, Q3 third quartile