Fig. 3From: Impact of tight glucose control on circulating 3-hydroxybutyrate in critically ill patientsAdmission and morning blood glucose concentrations (a), insulin dose (b), total caloric intake through enteral and parenteral nutrition (c) and serum 3-hydroxybutyrate (3HB) concentrations (d) during the first 3 days in the ICU in a matched subset of critically ill adults randomized to tight (dotted black line) or liberal (full gray line) glucose control. Data are shown as mean and standard error. Samples with undetectable 3HB concentrations were assigned the detection limit (0.04 mmol/L): 69 upon ICU admission (34 and 35 in tight and liberal group, respectively), 92 at day 1 (46 in each group), 94 at day 2 (46 and 48 in tight and liberal group, respectively) and 95 at day 3 (48 and 47 in tight and liberal group, respectively). *P ≤ 0.0001. For conversion of blood glucose in mg/dL to mmol/L, divide by 18Back to article page