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Table 2 Characteristics of patients with a positive Pneumocystis jirovecii qPCR

From: Pneumocystis pneumonia risk among viral acute respiratory distress syndrome related or not to COVID 19

Patient, age, sex

Underlying disease

Date of PCP diagnosis

Viral association

Respiratory sample

Direct examination (IFI or MGG)

Pneumocystis qPCR

BDG (pg/ml)*

Time between ICU admission and positive sample (day)

Treatment

P1, 58y, M

Diabetus mellitus

Congestive heart failure

14/01/2014

Coronavirus, Rhinovirus

BAL

Negative

36.7

NA

1

No

P2, 73y, M

Renal transplantation

Diabetus mellitus

Congestive heart failure

29/08/2015

Coronavirus

BAL

Positive

32

106

0

Yes (sulfamethoxazole)

P3, 52y, M

Myasthenia (steroid, azathioprine)

04/07/2012

Respiratory syncytial virus

BAL

Negative

39.8

NA

1

No

P4, 32y, F

Acute lymphoblastic leukemia (methotrexate and aracytabine)

08/01/2019

Metapneumovirus

BAL

Positive

27.9

188

0

Yes (sulfamethoxazole)

P5, 67y, M

Cirrhosis, rheumatoid polyarthritis (steroid)

22/04/2019

Coronavirus NL63

BAL

Negative

36.6

NA

1

No

  1. M = male, F = female, P = patient; BDG = (1–3)-β-D-glucan,*BDglucan not performed in the lab before 2013. BDglucan was performed using the Fungitell kit™ (Cape Cod Inc, USA) with a positivity threshold of 80 pg/mL; qPCR of P.jirovecii was performed using a region of the mitochondrial large subunit rRNA gene (LSU) after DNA extraction with a Qiasymphony kit (Qiagen, Courtaboeuf, France)