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Table 2 Long-term outcomes (three to six months after hospital discharge) of patients with conventional or facilitative weaning

From: Short and long-term outcomes of patients with COVID-19-associated acute respiratory distress syndrome and difficult veno-venous-ECMO weaning

  Facilitative weaning (n = 6) Conventional weaning (n = 7) P value
Pulmonary hypertensiona 0 (0) 0 (0)
Pulmonary function tests    
 KCO, % predicted 88 (75–100) 104 (88–111) 0.11
 DLCO, % predicted 57 (44–73) 70 (57–72) 0.29
 FVC % predicted 77 (59–85) 82 (52–91) 0.92
 TLC, % predicted 75 (65–79) 77 (64–94) 0.70
Chest CT-scan at long-term    
 Reticular pattern 1 (12) 1 (14) > 0.99
 Ground glass opacity 5 (71) 4 (50) 0.60
 Alveolar condensation 0 (0) 1 (12.5)  > 0.99
 Traction bronchiectasis 4 (57) 4 (50) > 0.99
 Tracheal traction 0 (0) 0 (0)
 Scissural distortion 2 (29) 1 (13) 0.57
6-min walking test    
 Walked distance, m 433 (348–503) 506 (480–548) 0.08
 % of predicted distance, % 67 (62–74) 90 (78–97) 0.009
 Room air saturation 97 (96–98) 98 (96–98) 0.82
Dyspnea (MRC scale)     0.07
 0 0 (0) 4 (57)  
 1 or 2 6 (100) 3 (43)  
  1. aAssessed by transthoracic echocardiography; KCO CO transfer coefficient; DLCO haemoglobin value (Hb) corrected diffusion capacity with CO; FVC forced expiratory vital capacity; TLC total lung capacity