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Table 2 Long-term outcomes (three to six months after hospital discharge) of patients with conventional or facilitative weaning

From: Short and long-term outcomes of patients with COVID-19-associated acute respiratory distress syndrome and difficult veno-venous-ECMO weaning

 

Facilitative weaning (n = 6)

Conventional weaning (n = 7)

P value

Pulmonary hypertensiona

0 (0)

0 (0)

Pulmonary function tests

   

 KCO, % predicted

88 (75–100)

104 (88–111)

0.11

 DLCO, % predicted

57 (44–73)

70 (57–72)

0.29

 FVC % predicted

77 (59–85)

82 (52–91)

0.92

 TLC, % predicted

75 (65–79)

77 (64–94)

0.70

Chest CT-scan at long-term

   

 Reticular pattern

1 (12)

1 (14)

> 0.99

 Ground glass opacity

5 (71)

4 (50)

0.60

 Alveolar condensation

0 (0)

1 (12.5)

 > 0.99

 Traction bronchiectasis

4 (57)

4 (50)

> 0.99

 Tracheal traction

0 (0)

0 (0)

 Scissural distortion

2 (29)

1 (13)

0.57

6-min walking test

   

 Walked distance, m

433 (348–503)

506 (480–548)

0.08

 % of predicted distance, %

67 (62–74)

90 (78–97)

0.009

 Room air saturation

97 (96–98)

98 (96–98)

0.82

Dyspnea (MRC scale)

  

 0.07

 0

0 (0)

4 (57)

 

 1 or 2

6 (100)

3 (43)

 
  1. aAssessed by transthoracic echocardiography; KCO CO transfer coefficient; DLCO haemoglobin value (Hb) corrected diffusion capacity with CO; FVC forced expiratory vital capacity; TLC total lung capacity