Table 1 Clinical characteristics of ARDS patients
Total | ARDSnet | University of Chicago | P value comparing ARDSnet and U of Chicago | |
|---|---|---|---|---|
N = 426 | N = 124 | N = 302 | ||
Age | 55.5 (42.1–66.6) | 51.0 (40.5–63.0) | 57.7 (42.4–67.7) | 0.007 |
Gender | ||||
Male | 227 (53.3%) | 68 (54.8%) | 159 (52.6%) | 0.68 |
Female | 199 (46.7%) | 56 (45.2%) | 143 (47.4%) | |
Race | < 0.001 | |||
White | 188 (44.1%) | 88 (71.0%) | 100 (33.1%) | |
Hispanic | 21 ( 4.9%) | 11 ( 8.9%) | 10 ( 3.3%) | |
African American | 196 (46.0%) | 25 (20.2%) | 171 (56.6%) | |
Asian | 9 (2.1%) | 0 (0.0%) | 9 (3.0%) | |
Other | 12 (2.8%) | 0 (0.0%) | 12 (4.0%) | |
SOFA | 9.0 (7.0–12.0) | 10.0 (7.5–13.0) | 9.0 (7.0–12.0) | 0.085 |
APACHE II | NA | NA | 29 (23–36) | |
APACHE III | NA | 90 (72–113)* | NA | |
PaO2:FiO2 | 136.0 (92.8–197.5) | 176.6 (134.0–235.8) | 120.0 (81.0–178.0) | < 0.001 |
Tidal volume | 420.0 (362.0–460.0) | 427.5 (360.0–480.0) | 420.0 (370.0–450.0) | 0.71 |
TV ml/kg IBW | 6.4 (5.8–7.2) | 6.5 (6.0–7.4) | 6.3 (5.7–7.1) | 0.002 |
Hospital mortality | 199 (46.7%) | 26 (21.0%) | 173 (57.3%) | < 0.001 |