Table 1 Keeping and abandoning ARDS: advantages and disadvatages
Keep and modify ARDS definition | Abandon ARDS definition | |
|---|---|---|
Advantages | Easy patient categorization and labeling Facilitated enrollment in RCTs Standardized guidance of treatment | Recognizes need to personalize therapy Focuses on patient-relevant characteristics Encourages best responses to ∆’s over time |
Drawbacks | Non-uniformity encourages inappropriate Rx Promotes RCT enrollment of unqualified Pts May inform misleading treatment guidelines | Universal standards for Rx difficult to establish Precision inhibits RCT design and enrollment Often requires mastery of bedside physiology |