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Table 4 Outcome data in matched patients with and without prehospital TXA administration

From: The impact of prehospital tranexamic acid on mortality and transfusion requirements: match-pair analysis from the nationwide German TraumaRegister DGU®

 

Tranexamic acid group

Control group

p value

ICU LOS (days) median, IQR

7 (2–18)

7 (2–18)

.125

Hospital LOS (days) median, IQR

19 (8–32)

18 (8–31)

.238

Thromboembolic event (n, %)

132 (6.1%)

100 (4.9%)

.080

Sepsis (n, %)

277 (13.3%)

249 (12.7%)

.570

Multiple organ failure (n, %)

843 (40.0%)

870 (42.6%)

.087

Time to death (days) median, IQR

2 (1–8)

2 (1–6)

.933

6-h mortality (n, %)

155 (6.8%)

208 (9.1%)

.004

12-h mortality (n, %)

239 (10.5%)

282 (12.4%)

.045

24-h mortality (n, %)

297 (13.1%)

333 (14.6%)

.122

30-day mortality (n, %)

510 (22.4%)

524 (23.0%)

.620

In-hospital mortality (n, %)

531 (23.3%)

553 (24.3%)

.444

Expected mortality rate based on RISC II prognosis (%)

24.8%

25.1%

.680

Death due to hemorrhage (n, %)

68 (3.0)

97 (4.3)

.021

  1. ICU, intensive care unit; LOS, length of stay