Table 3 Clinical characteristics upon hospital admission of matched trauma patients with and without tranexamic acid administered during the prehospital phase
Tranexamic acid group n = 2275 | Control group n = 2275 | p value | |
|---|---|---|---|
Shock (BP ≤ 90 mmHg) (n, %) | 539 (24.6%) | 571 (26.4) | .185 |
BP on admission (mmHg), mean, SD | 113 (34) | 111 (35) | .108 |
Hemoglobin (g/dl), mean, SD | 11.6 (2.7) | 11.7 (2.7) | .305 |
Base excess (mmol/l) mean, SD | − 4.5 (6.1) | − 4.3 (6.3) | .155 |
INR mean, SD | 1.32 (0.67) | 1.32 (0.75) | .094 |
Fluids (ml) median, IQR | 1500 (500–3000) | 1000 (500–2150) | < .001 |
Blood transfusion until ICU (n, %)b | 765 (33.9%) | 694 (30.7%) | .022 |
FFP transfusion until ICU (n, %) | 462 (20.5%) | 435 (19.3%) | .307 |
Units of pRBCa, median, IQR | 4 (2–7) | 4 (2–9) | < .001 |
Units of FFPa, median, IQR | 2 (0–6) | 3 (0–7) | .023 |
Units of pRBCb, median, IQR | 0 (0–2) | 0 (0–2) | .235 |
Units of FFPb, median, IQR | 0 (0–0) | 0 (0–0) | .501 |
Hemostatic drugsc (n, %) | 1034 (47.8%) | 939 (44.2%) | .018 |
TXA in the ER (n, %) | 749 (32.9) | 798 (35.1) | .014 |