Table 2 Logistic regression model with prehospital administration of tranexamic acid as a dependent variable for generation of propensity score (n = 15,652)
Variable | Regression coefficient | OR (95% CI) | p Value |
|---|---|---|---|
Age (ref: < 60 years) | < 0.001 | ||
60–69 years | − 0.17 | 0.84 (0.73–0.97) | 0.020 |
70–79 years | − 0.36 | 0.70 (0.59–0.82) | < 0.001 |
80 + years | − 0.42 | 0.66 (0.54–0.79) | < 0.001 |
Penetrating trauma | 0.52 | 1.68 (1.40–2.02) | < 0.001 |
Severe head injury (AIS 3 +) | 0.05 | 1.06 (0.94–1.18) | 0.37 |
Severe abdominal trauma (AIS 3 +) | 0.24 | 1.27 (1.13–1.42) | < 0.001 |
Severe extremity injuries (AIS 3 +) | 0.46 | 1.58 (1.43–1.75) | < 0.001 |
Prehospital intubation | 0.59 | 1.80 (1.58–2.05) | < 0.001 |
Prehospital catecholamines | 0.49 | 1.63 (1.44–1.84) | < 0.001 |
Chest tube insertion | 0.66 | 1.94 (1.68–2.25) | < 0.001 |
Glasgow Coma Scale (ref: 14–15) | 0.005 | ||
9–13 | 0.09 | 1.09 (0.95–1.26) | 0.22 |
3–8 | − 0.10 | 0.90 (0.78–1.05) | 0.17 |
Not documented | − 0.41 | 0.66 (0.49–0.91) | 0.010 |
First systolic BP (ref: > 90 mmHg) | 0.011 | ||
71–90 mmHg | 0.16 | 1.18 (1.03–1.35) | 0.020 |
1–70 mmHg | 0.25 | 1.29 (1.08–1.54) | < 0.005 |
not documented | 0.03 | 1.03 (0.86–1.24) | 0.75 |
Prehospital volume (ref: 0–500) | < 0.001 | ||
501–1000 ml | 0.53 | 1.70 (1.49–1.94) | < 0.001 |
1001–2000 ml | 0.93 | 2.54 (2.21–2.92) | < 0.001 |
> 2000 ml | 1.07 | 2.91 (2.38–3.55) | < 0.001 |
Not documented | − 0.09 | 0.92 (0.72–1.17) | 0.48 |
Mechanism: traffic | 0.37 | 1.45 (1.26–1.66) | < 0.001 |
Mechanism: high fall | 0.24 | 1.28 (1.08–1.58) | 0.004 |
Helicopter transport | 0.98 | 2.66 (2.41–2.94) | < 0.001 |
Constant | − 3.61 | < 0.001 |