Table 1 Characteristics of patients with sepsis
Characteristics | All patients | Fluid overload | No fluid overload |
|---|---|---|---|
N (males/females) | 25 (19/6) | 11 (10/1) | 14 (9/5) |
Age (years) | 67.0 (32–86) | 68.2 (46–86) | 66.0 (32–82) |
Body weight (kg) | 84.8 (59–120) | 85.3 (70–113) | 84.4 (59–120) |
BMI (kg/m2) | 28.7 (21.6–41.5) | 28.0 (21.6–34.1) | 29.2 (21.7–41.5) |
Source of infection (n, %) | |||
Respiratory | 12 (48%) | 1 (9%) | 11 (79%) |
Intra-abdominal | 9 (36%) | 8 (73%) | 1 (7%) |
Soft tissue | 4 (16%) | 2 (18%) | 2 (14%) |
Septic shock (n, %) | 18 (72%) | 9 (82%) | 9 (64%) |
Noradrenaline (n, %) | 21 (84%) | 9 (82%) | 12 (86%) |
Median (IQR) dose | 11.8 (2.6–29.5) | 6.9 (0.4–36.9) | 13.6 (2.8–29.5) |
Furosemide (n, %) | 24 (96%) | 11 (100%) | 12 (86%) |
Median (IQR) dose | 142 (81–220) | 170 (125–253) | 98 (67–208) |
CLcr (ml/min/1.73 m2)a | 81.5 (21–174) | 82.1 (21–174) | 81.2 (26–157) |
APACHE II | 20.2 (11–33) | 21.1 (12–27) | 19.6 (11–33) |
SOFA | 7.4 (2–13) | 7.0 (3–13) | 7. 7 (2–12) |
Surgery (n, %) | 17 (68%) | 11 (100%) | 6 (43%) |
Mechanical ventilation (n, %) | 24 (96%) | 11 (100%) | 13 (93%) |
Days of MV | 9.3 (0–43) | 4.4 (2–10) | 12 (0–43) |
Days of AT | 9.2 (3–15) | 11.5 (8–15) | 7.2 (3–15) |
Mortality | 6 (24%) | 1 (9%) | 5 (36%) |