Fig. 1From: Impact of cumulative fluid balance on the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsisAssayed concentrations of meropenem vs. the sampling interval relative to the start of the last infusion. The patients were infused with 2 g meropenem as 3-h infusions every 8 h. For the 3 patients receiving 1 g, the concentrations recalculated to the dose of 2 g are shown. Solid lines are means and dotted lines depict concentrations equal to the MICs of 2 and 8 mg/LBack to article page