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Table 1 Characteristics and ventilatory parameters at inclusion of the matched patients with COVID-19 and pulmonary non-COVID-19 ARDS

From: Longitudinal changes in compliance, oxygenation and ventilatory ratio in COVID-19 versus non-COVID-19 pulmonary acute respiratory distress syndrome

 

COVID-19 patients

n = 112

Pulmonary non-COVID-19 ARDS patients

n = 198

p value

Age, years

63 [51–72]

60 [48–71]

0.196

SAPS II

47 [37–58]

48 [37–59]

0.562

Female sex, n

36 (32)

50 (25)

0.193

BMI, kg m−2

29 [26–33]

26 [23–29]

< 0.001

ARDS severity, n

   

 Mild

20 (18)

51 (26)

0.112

 Moderate

66 (59)

117 (59)

0.978

 Severe

26 (23)

30 (15)

0.706

Tidal volume, ml kg−1 PBW

6.1 [5.9–6.9]

6.9 [6.1–8.1]

< 0.001

Respiratory rate, cycles min−1

27 [25–30]

30 [25–35]

< 0.001

Volume minute, L min−1

10.5 [9.3–11.8]

11.7 [10–14]

< 0.001

PaCO2, mmHg

38 [34–43]

43 [37–49]

< 0.001

PEEP set, cmH2O

12 [10–14]

10 [9–12]

0.072

Plateau pressure, cmH2O

24 [20–27]

25 [22–28]

0.655

Respiratory system compliance, ml cmH2O−1

35 [28–43]

28 [23–36]

 < 0.001

PaO2/FiO2, mmHg

143 [103–184]

134 [98–178]

0.404

A-a O2 gradient, mmHg

347 [242–514]

351 [271–485]

0.554

Ventilatory ratio

1.5 [1.3–2.0]

2.0 [1.6–2.6]

< 0.001

Cause of lung injury, n

   

 COVID-19

112 (100)

 Pneumonia

151 (76)

 Aspiration

47 (24)

  1. SAPS II, simplified acute physiology score II; BMI, body mass index; PBW, predicted body weight; PEEP, positive end expiratory pressure; PaO2, partial pressure of arterial oxygen; FiO2, fraction of inspired oxygen; A-a O2 gradient, alveolar-arterial oxygen gradient; PaCO2, partial pressure of arterial carbon dioxide. Results are presented as median [interquartile range] or number (%)