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Table 1 Regression analysis for the outcomes

From: Evaluation of thiamine as adjunctive therapy in COVID-19 critically ill patients: a two-center propensity score matched study

Outcomes

Before propensity score

After propensity score

 

Control (650 patients)

Thiamine (88 patients)

P value

Odds Ratio (OR) (95% CI)

P value

Control (83 patients)

Thiamine (83 patients)

P value

Odds ratio (OR) (95% CI)

P value

30-day mortality, n (%)#

264 (40.6)

18 (20.5)

0.002^^

0.45 (0.24,0.84)

0.01*^

30 (36.1)

15 (18.1)

0.009^^

0.37 (0.18,0.78)

0.009$

In-hospital mortality, n (%)#

313 (48.2)

22 (25)

0.009^^

0.37 (0.18,0.78)

0.009*^

35 (42.2)

19 (22.9)

0.008^^

0.39 (0.19,0.78)

0.008$

    

Beta coefficient (95% CI)

P value

   

Beta coefficient (95% CI)

P value

MV duration during ICU, Median (Q1, Q3) &#

10.0 (4.0, 17.0)

7.0 (3.0, 16.0)

0.17^

0.02 (− 0.24, 0.30)

0.84*^

11.0 (5.0, 20.0)

7.0 (3.0, 20.0)

0.68^

− 0.13 (− 0.54, 0.27)

0.51$*

ICU Length of Stay (Days), Median (Q1, Q3) &

8.0 (5.0, 14.0)

8.0 (5.0,13.0)

0.89^

0.07 (− 0.12, 0.27)

0.49*^

8.0 (4.0, 12.0)

8.0 (5.0, 13.0)

0.78^

0.11 (− 0.19, 0.39)

0.48$*

Hospital Length of Stay (Days), Median (Q1, Q3)&

17.0 (11.0, 26.5)

15.0 (10.0, 24.5)

0.47^

0.04 (− 0.12,0.21)

0.59*^

13.0 (11.0, 21.0)

15.0 (10.0, 25.0)

0.30^

0.08 (− 0.17,0.33)

0.52$*

  1. #Denominator of the percentage is the total number of patients
  2. ^Wilcoxon rank sum test is used to calculate the P value
  3. ^^Chi-square test is used to calculate the P value
  4. $*Propensity score adjusted negative binomial regression is used to calculate the beta coefficient (estimates) and P value
  5. $Propensity score adjusted logistic regression is used to calculate odds ratio and P value
  6. *^Multivariable logistic regression is used after adjusting for patient’s baseline severity scores, systemic use of corticosteroids and study centers to calculate odds ratio and P value
  7. &Denominator is patients who survived
  8. &#Denominator is patients who have respiratory failure requiring MV during ICU stay