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Table 2 Clinical characteristics and echocardiographic findings of ARDS patients eligible for ECMO

From: Evaluation of right ventricular function and driving pressure with blood gas analysis could better select patients eligible for VV ECMO in severe ARDS

Characteristics, outcomes and complications

Survivors

(n = 36)

Non survivors

(n = 31)

p-value

Age (years)

56 (45–70)

57 (48–70)

0.44

Male sex, n (%)

23 (64)

19 (61)

0.47

SAPS II

44 (32–58)

53 (36–75)

0.15

Weight (kg)

74 (63–97)

67 (56–80)

0.22

Cause of ARDS, n (%)

  

0.63

 Pneumonia

6 (17)

2 (7)

 

 Aspiration

18 (50))

16 (53)

 

 Non-pulmonary sepsis

8 (22)

9 (30)

 

 Other causes

4 (11)

3 (10)

 

Respiratory setting at inclusion

   

 Tidal volume (ml/kg)

6.3 (5.5–7.6)

5.9 (5.3–6.6)

0.13

 Respiratory rate (cycle/min)

25 (20–27)

30 (25–30)

 < 0.01

 PEEP (cmH2O)

10 (8–12)

10 (7–12)

0.72

 Plateau pressure (cmH2O)

26 (24–29)

28 (25–38)

0.07

 Compliance (ml/cmH2O)

30 (2338)

23 (16–28)

 < 0.01

 Driving pressure (cmH2O)

16 (14–19)

19 (16–22)

0.05

Arterial blood gases

   

 PaO2/FiO2 ratio (mmHg)

69 (58–74)

60 (55–67)

0.08

 PaCO2 (mmHg)

48 (40–52)

51 (42–70)

0.17

Shock, n (%)

25 (70)

28 (90)

0.07

Prone positioning, n (%)

31 (86)

24 (77)

0.52

VV ECMO in rescue during ARDS course, n (%)

2 (1)

6 (19)

0.13

RRT during ARDS course, n (%)

9 (33)

6 (55)

0.28

Echocardiographic findings

   

 RVEDA/LVEDA

0.71 (0.57–0.93)

0.98 (0.71–1.10)

0.10

 Pulmonary hypertension (mmHg)

51 (44–55)

52 (34–63)

0.85

 Severe acute cor pulmonale

3 (8)

8 (26)

0.09

 ICU stay (days)

19 (14–34)

12 (3–20)

0.16

  1. Values are expressed as median (interquartile range) or n (%)
  2. ARDS, Acute Respiratory Distress Syndrome; PEEP, Positive End-Expiratory Pressure; VV ECMO, Veno-Venous Extracorporeal Membrane Oxygenation; RRT, Renal Remplacement Therapy; RVEDA, Right Ventricular End-Diastolic Area; LVDEA, Left Ventricular End-Diastolic Area; ICU, Intensive Care Unit