Characteristics, outcomes and complications | Survivors (n = 36) | Non survivors (n = 31) | p-value |
---|---|---|---|
Age (years) | 56 (45–70) | 57 (48–70) | 0.44 |
Male sex, n (%) | 23 (64) | 19 (61) | 0.47 |
SAPS II | 44 (32–58) | 53 (36–75) | 0.15 |
Weight (kg) | 74 (63–97) | 67 (56–80) | 0.22 |
Cause of ARDS, n (%) | 0.63 | ||
Pneumonia | 6 (17) | 2 (7) | |
Aspiration | 18 (50)) | 16 (53) | |
Non-pulmonary sepsis | 8 (22) | 9 (30) | |
Other causes | 4 (11) | 3 (10) | |
Respiratory setting at inclusion | |||
Tidal volume (ml/kg) | 6.3 (5.5–7.6) | 5.9 (5.3–6.6) | 0.13 |
Respiratory rate (cycle/min) | 25 (20–27) | 30 (25–30) | < 0.01 |
PEEP (cmH2O) | 10 (8–12) | 10 (7–12) | 0.72 |
Plateau pressure (cmH2O) | 26 (24–29) | 28 (25–38) | 0.07 |
Compliance (ml/cmH2O) | 30 (2338) | 23 (16–28) | < 0.01 |
Driving pressure (cmH2O) | 16 (14–19) | 19 (16–22) | 0.05 |
Arterial blood gases | |||
PaO2/FiO2 ratio (mmHg) | 69 (58–74) | 60 (55–67) | 0.08 |
PaCO2 (mmHg) | 48 (40–52) | 51 (42–70) | 0.17 |
Shock, n (%) | 25 (70) | 28 (90) | 0.07 |
Prone positioning, n (%) | 31 (86) | 24 (77) | 0.52 |
VV ECMO in rescue during ARDS course, n (%) | 2 (1) | 6 (19) | 0.13 |
RRT during ARDS course, n (%) | 9 (33) | 6 (55) | 0.28 |
Echocardiographic findings | |||
RVEDA/LVEDA | 0.71 (0.57–0.93) | 0.98 (0.71–1.10) | 0.10 |
Pulmonary hypertension (mmHg) | 51 (44–55) | 52 (34–63) | 0.85 |
Severe acute cor pulmonale | 3 (8) | 8 (26) | 0.09 |
ICU stay (days) | 19 (14–34) | 12 (3–20) | 0.16 |