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Table 1 Clinical characteristics and outcome of the entire cohort according to EOLIA criteria

From: Evaluation of right ventricular function and driving pressure with blood gas analysis could better select patients eligible for VV ECMO in severe ARDS

Characteristics, outcomes and complications ARDS patients without EOLIA criteria
(n = 685)
ARDS patients with EOLIA criteria
(n = 67)
p-value
Age (years) 59 (47–72) 56 (47–70) 0.43
Male sex, n (%) 465 (68) 42 (63) 0.47
SAPS II 51 (38–65) 47 (33–64) 0.27
Weight (kg) 77 (65–84) 70 (59–86) 0.43
Cause of ARDS, n (%)    0.20
 Pneumonia 83 (12) 8 (12)  
 Aspiration 259 (39) 34 (51))  
 Non-pulmonary sepsis 245 (37) 17 (26)  
 Other causes 83 (12) 7 (11)  
Respiratory setting at inclusion    
 Tidal volume (ml/kg) 6.7 (6.0–8.0) 6.02 (5.4–6.9)  < 0.01
 Respiratory rate (cycle/min) 22 (16–27) 26 (22–30)  < 0.01
 PEEP (cmH2O) 8 (5–10) 10 (7–12)  < 0.01
 Plateau pressure (cmH2O) 24 (21–28) 27 (25–29)  < 0.01
 Compliance (ml/cmH2O) 30.7 (24–39.1) 25.9 (19.3–33.8)  < 0.01
 Driving pressure (cmH2O) 15 (13–19) 17 (14–19.8) 0.04
Arterial blood gases    
 PaO2/FiO2 ratio (mmHg) 114 (90–120) 62 (55–72)  < 0.01
 PaCO2 (mmHg) 44 (38–52) 48 (41–60)  < 0.01
Shock, n (%) 449 (66) 53 (79) 0.04
Prone positioning, n (%) 163 (24) 55 (82)  < 0.01
VV ECMO in rescue during ARDS course, n (%) 0 (0) 8 (12)  < 0.01
RRT during ARDS course, n (%) 126 (30) 15 (40) 0.27
Echocardiographic findings    
RVEDA/LVEDA 0.68 (0.57–0.81) 0.83 (0.64–1.04)  < 0.01
 Systolic pulmonary artery pressure (mmHg) 35 (20–48) 52 (35–59)  < 0.01
 Severe acute cor pulmonale 43 (6) 11 (16)  < 0.01
Outcome, n (%)    
 ICU mortality 243 (36) 31 (46) 0.10
 ICU stay (days) 16 (8–30) 15 (6–31) 0.43
  1. Values are expressed as median (interquartile range) or n (%)
  2. ARDS, Acute Respiratory Distress Syndrome; PEEP, Positive End-Expiratory Pressure; VV ECMO, Veno-Venous Extracorporeal Membrane Oxygenation; RRT, Renal Remplacement Therapy; RVEDA, Right Ventricular End-Diastolic Area; LVDEA, Left Ventricular End-Diastolic Area; ICU, Intensive Care Unit