Skip to main content

Table 1 Clinical and instrumental characteristic of study population

From: SARS-COV-2 colonizes coronary thrombus and impairs heart microcirculation bed in asymptomatic SARS-CoV-2 positive subjects with acute myocardial infarction

 

Asymptomatic SARS-COV-2 Positive patients (N= 46)

SARS-COV-2 Negative patients (N = 130)

P

Age, years

56.13 ± 6.21

68.43 ± 6.46

0.006

Male, n (%)

31 (67.4)

86 (66.2)

0.515

BMI (kg/m2)

27.09 ± 1.81

29.55 ± 1.97

0.003

Diabetes, n (%)

8 (17.4)

38 (29.2)

0.478

Dyslipidemia, n (%)

7 (15.2)

30 (23.7)

0.181

Hypertension, n (%)

18 (39.1)

72 (55.4)

0.042

Smoking, n (%)

3 (6.5)

39 (29.2)

0.001

Acetylsalicylic acid, n (%)

21 (45.6)

60 (46.1)

0.546

Ace-inhibitors, n (%)

15 (32.6)

45 (34.6)

0.477

AT II receptor blocker

6 (13.1)

25 (19.2)

0.239

Insulin, n (%)

2 (4.3)

5 (3.8)

0.587

Oral anti-diabetic drugs, n (%)

6 (13.1)

30 (23.1)

0.106

Statin, n (%)

7 (15.2)

27 (20.8)

0.278

Glycemia (mg/dl)

129.65 ± 21.02

129.22 ± 27.64

0.924

Cholesterol (mg/dl)

181.2 ± 21.4

197.7 ± 21.1

0.001

LDL-cholesterol (mg/dl)

111.57 ± 21.65

123.83 ± 20.43

0.010

Triglycerides (mg/dl)

163.91 ± 23.63

181.79 ± 18.06

0.001

LDH (unit/l)

367.83 ± 37.41

375.46 ± 33.32

0.126

Creatinine (mg/dl)

0.92 ± 0.22

1.04 ± 0.14

0.001

Fibrinogen (g/l)

3.68 ± 0.37

3.75 ± 0.33

0.198

White cells count (109/l)

15.76 ± 1.27

12.49 ± 4.82

0.002

Lymphocyte (109/l)

1.76 ± 0.20

1.80 ± 0.14

0.130

Virus load CT, n

26.02 ± 2.22

/

/

Thrombus virus load CT, n

25.46 ± 8.68

/

/

Ejection fraction (%)

41.49 ± 1.82

47.25 ± 3.55

0.003

LAD, n (%)

31 (67.4)

74 (56.9)

0.091

LMS, n (%)

8 (17.4)

15 (11.3)

0.145

Cx, n (%)

5 (10.9)

13 (10.0)

0.520

RCA, n (%)

12 (26.1)

39 (30.0)

0.349

GP IIb/IIIa inhibitor, n (%)

25 (54.3)

19 (14.6)

0.006

Multi-vessel PCI, n (%)

10 (21.7)

11 (8.5)

0.020

Thrombus dimension, mm2

4.21 ± 1.12

2.71 ± 0.42

0.001

Modified thrombus G 5, n (%)

41 (89.1)

30 (23.1)

0.001

Multivessel thrombus, n (%)

16 (34.8)

12 (9.2)

0.001

Post-PPCI TIMI 3, n (%)

43 (93.5)

124 (95.4)

0.432

Blush grade 2–3, n (%)

12 (26.1)

127 (97.7)

0.001

Total heparin dose, U

12777.78 ± 356

10137.55 ± 299

0.047

Door-to-balloon time (min)

54 (38–72)

51 (35.3–57.9)

0.345

Average ACT

268.7 ± 67.2

271.6 ± 59.3

0.167

MACE

   

Death, n (%)

4 (8.7)

2 (1.5)

0.041

Non-fatal AMI, n (%)

6 (13.0)

4 (3.1)

0.021

Heart failure, n (%)

4 (8.7)

3 (2.3)

0.077

  1. Data are means ± SD or n (%)
  2. BMI, body mass index; CT, cycle threshold; LAD, left anterior descending artery; LMS, left main coronary artery; MACE, major adverse cardiac events; Cx, circumflex artery; RCA, right coronary artery; ACT, activated clotting time; AMI, acute myocardial infarction