Table 2 Univariate mixed model with random intercept of factors associated with the occurrence of psychological sequelae during follow-up

Predicting insomnia in follow-up

History of sleep disorders

4.24

[− 0.54;9.08]

0.082

Acute respiratory distress syndrome

0.099

 Mild

Reference

Reference

 Moderate

1.32

[− 2.46;5.09]

 Severe

4.87

[0.35;9.34]

Cumulative dose of morphine (for 1000 units)

0.74

[− 0.06;1.53]

0.069

Cumulative dose of midazolam (for 100 units)

1.41

[0.44;2.39]

0.007

Cumulative dose of clonidine (for 1 unit)

1.29

[0.24;2.36]

0.020

Maximal dose of norepinephrine

− 2.78

[− 11.5;5.98]

0.520

Length of ICU stay (for 10 days)

1.02

[0.14;1.90]

0.025

Predicting anxiety in follow-up

History of sleep disorders

0.98

[− 1.87;3.78]

0.488

Acute respiratory distress syndrome

0.206

 Mild

Reference

Reference

 Moderate

0.75

[− 1.39;2.94]

 Severe

2.36

[− 0.30;4.97]

Cumulative dose of morphine (for 1000 units)

0.15

[− 0.45;0.76]

0.612

Cumulative dose of midazolam (for 100 units)

0.02

[− 0.12;0.07]

0.537

Cumulative dose of clonidine (for 1 unit)

0.43

[− 0.12;0.98]

0.118

Maximal dose of norepinephrine

− 2.61

[− 7.64;2.44]

0.301

Length of ICU stay (for 10 days)

0.46

[− 0.07;0.99]

0.091

Predicting depression in follow-up

History of sleep disorders

1.19

[− 2.09;4.41]

0.464

Acute respiratory distress syndrome

0.823

 Mild

Reference

Reference

 Moderate

0.75

[− 1.89;3.42]

 Severe

0.81

[− 2.43;3.99]

Cumulative dose of morphine (for 1000 units)

0.05

[− 0.60;0.69]

0.883

Cumulative dose of midazolam (for 100 units)

0.02

[− 0.05;0.09]

0.588

Cumulative dose of clonidine (for 1 unit)

0.57

[0.11;1.03]

0.019

Maximal dose of norepinephrine

− 2.82

[− 8.11;2.54]

0.292

Length of ICU stay (for 10 days)

0.39

[− 0.23;1.01]

0.208

Predicting post-traumatic stress disorder in follow-up

History of sleep disorders

8.36

[− 1.60;18.4]

0.100

Acute respiratory distress syndrome

0.059

 Mild

Reference

Reference

 Moderate

0.55

[− 7.13;8.17]

 Severe

9.81

[1.06;18.5]

Cumulative dose of morphine (for 1000 units)

0.21

[− 1.77;2.17]

0.826

Cumulative dose of midazolam (for 100 units)

0.16

[− 0.04;0.35]

0.103

Cumulative dose of clonidine (for 1 unit)

0.93

[− 1.14;3.01]

0.363

Maximal dose of norepinephrine

5.71

[− 9.65;21.0]

0.449

Length of ICU stay (for 10 days)

1.54

[− 0.37;3.42]

0.109