Outcome | Study group | P value | |
---|---|---|---|
NIV success (n = 8) | NIV failure (n = 10) | ||
Diaphragm thickening fraction (%) | |||
 At the enrolment | 35 [25.8–67.4] | 41.5 [22–56] | 0.864 |
 1 h after the enrolment | 37.9 [25.2–50.9] | 30.1 [17.8–43.6] | 0.41 |
 4 h after the enrolment | 54.2 [41–72.6] | 28.2 [19.2–53.8] | 0.114 |
 12 h after the enrolment | 53 [39.3–74] | 27.4 [21.9–34.5] | 0.032 |
 24 h after the enrolment | 55.1 [38–80.9] | 33.3 [26.9–63.9] | 0.114 |
 48 h after the enrolment | 43.3 [39–54.4] | 32.5 [23.8–32.5] | 0.067 |
 72 h after the enrolment | 47.5 [39–56] | 19.7 [15.1–19.7] | 0.383 |
 96 h after the enrolment | 56.9 [45.7–80.3] | 23.3 [15.8–23.3] | 0.071 |
Respiratory rate/Diaphragm thickening fraction | |||
 At the enrolment | 1.19 [0.84–1.55] | 1.09 [0.73–2.42] | 0.776 |
 1 h after the enrolment | 0.69 [0.64–1.24] | 1.16 [0.61–1.61] | 0.315 |
 4 h after the enrolment | 0.40 [0.32–0.78] | 1.21 [0.66–1.99] | 0.008 |
 12 h after the enrolment | 0.33 [0.27–0.55] | 1.39 [0.83–2.00] | 0.008 |
 24 h after the enrolment | 0.40 [0.29–0.43] | 0.75 [0.42–1.32] | 0.114 |
 48 h after the enrolment | 0.42 [0.31–0.60] | 0.78 [0.69–0.78] | 0.033 |
 72 h after the enrolment | 0.34 [0.32–0.58] | 1.07 [0.65–1.07] | 0.017 |
 96 h after the enrolment | 0.34 [0.23–0.37] | 0.99 [0.71–0.99] | 0.036 |
PaO2/FiO2 ratio (mmHg) | |||
 At the enrolment | 87 [75–92] | 103 [76–148] | 0.36 |
 1 h after the enrolment | 197 [164–301] | 140 [112–221] | 0.083 |
 4 h after the enrolment | 256 [165–423] | 189 [132–246] | 0.20 |
 12 h after the enrolment | 245 [152–309] | 133 [115–177] | 0.022 |
 24 h after the enrolment | 214 [184–406] | 173 [134–204] | 0.154 |
 48 h after the enrolment | 256 [197–282] | 158 [121–158] | 0.117 |
 72 h after the enrolment | 246 [199–382] | 172 [165–172] | 0.517 |
 96 h after the enrolment | 261 [225–395] | 162 [152–162] | 0.517 |
PaCO2 (mmHg) | |||
 At the enrolment | 31 [29–49] | 30 [25–39] | 0.515 |
 1 h after the enrolment | 34 [30–41] | 32 [24–42] | 0.696 |
 4 h after the enrolment | 32 [30–37] | 30 [25–44] | 0.673 |
 12 h after the enrolment | 31 [30–34] | 34 [28–44] | 0.445 |
 24 h after the enrolment | 32 [28–36] | 31 [28–35] | 0.683 |
 48 h after the enrolment | 32 [29–35] | 34 [32–34] | 0.383 |
 72 h after the enrolment | 32 [30–45] | 40 [33–40] | 0.517 |
 96 h after the enrolment | 44 [28–48] | 37 [35–37] | 0.883 |
Respiratory rate, breaths per minute | |||
 At the enrolment | 38 [36–48] | 38 [36–46] | 0.96 |
 1 h after the enrolment | 29 [23–36] | 26 [19–34] | 0.51 |
 4 h after the enrolment | 22 [19–28] | 30 [25–38] | 0.036 |
 12 h after the enrolment | 22 [16–25] | 29 [27–34] | 0.020 |
 24 h after the enrolment | 21 [16–26] | 26 [22–34] | 0.154 |
 48 h after the enrolment | 18 [15–22] | 25 [25–25] | 0.012 |
 72 h after the enrolment | 18 [18–21] | 21 [20, 21] | 0.133 |
 96 h after the enrolment | 18 [15–20] | 23 [16–23] | 0.279 |