|
n
|
7487
|
319
|
756
|
1723
|
1446
|
1097
|
1127
|
730
|
246
|
43
|
|
Male sex (n, %)
|
3934 (52.5)
|
200 (62.7)
|
455 (60.2)
|
988 (57.3)
|
783 (54.1)
|
530 (48.3)
|
504 (44.7)
|
333 (45.6)
|
122 (49.6)
|
19 (44.2)
|
|
Age, years (median [IQR])
|
84.0 [81.0, 87.0]
|
82.0 [81.0, 85.0]
|
83.0 [81.0, 86.0]
|
83.0 [81.0, 86.0]
|
84.0 [81.0, 86.0]
|
84.0 [82.0, 87.0]
|
84.0 [82.0, 88.0]
|
85.0 [82.0, 88.0]
|
84.0 [82.0, 87.0]
|
83.0 [81.0, 87.0]
|
|
SOFA score (median [IQR])
|
7.0 [4.0, 10.0]
|
6.0 [3.0, 8.0]
|
6.0 [4.0, 10.0]
|
6.0 [4.0, 10.0]
|
6.0 [4.0, 10.0]
|
7.0 [4.0, 10.0]
|
7.0 [4.0, 10.0]
|
8.0 [5.0, 10.0]
|
9.0 [6.0, 12.0]
|
9.0 [7.5, 12.5]
|
|
Reason for admission (n, %)
|
|
Respiratory failure
|
1809 (24.2)
|
67 (21.0)
|
154 (20.4)
|
358 (20.8)
|
374 (25.9)
|
278 (25.3)
|
300 (26.6)
|
191 (26.2)
|
73 (29.7)
|
14 (32.6)
|
|
Circulatory failure
|
1057 (14.1)
|
32 (10.0)
|
111 (14.7)
|
240 (13.9)
|
221 (15.3)
|
157 (14.3)
|
166 (14.7)
|
100 (13.7)
|
23 (9.3)
|
7 (16.3)
|
|
Combined respiratory/circulatory failure
|
874 (11.7)
|
17 (5.3)
|
58 (7.7)
|
165 (9.6)
|
183 (12.7)
|
137 (12.5)
|
141 (12.5)
|
116 (15.9)
|
50 (20.3)
|
7 (16.3)
|
|
Sepsis
|
992 (13.2)
|
26 (8.2)
|
80 (10.6)
|
242 (14.0)
|
159 (11.0)
|
162 (14.8)
|
152 (13.5)
|
119 (16.3)
|
45 (18.3)
|
7 (16.3)
|
|
Emergency surgery
|
900 (12.0)
|
49 (15.4)
|
96 (12.7)
|
246 (14.3)
|
166 (11.5)
|
131 (11.9)
|
137 (12.2)
|
60 (8.2)
|
14 (5.7)
|
1 (2.3)
|
|
Non-traumatic cerebral pathology
|
477 (6.4)
|
38 (11.9)
|
67 (8.9)
|
104 (6.0)
|
84 (5.8)
|
52 (4.7)
|
68 (6.0)
|
48 (6.6)
|
12 (4.9)
|
4 (9.3)
|
|
Multiple trauma without head injury
|
141 (1.9)
|
12 (3.8)
|
28 (3.7)
|
39 (2.3)
|
25 (1.7)
|
14 (1.3)
|
18 (1.6)
|
5 (0.7)
|
0 (0.0)
|
0 (0.0)
|
|
Multiple trauma with head injury
|
128 (1.7)
|
15 (4.7)
|
24 (3.2)
|
36 (2.1)
|
18 (1.2)
|
18 (1.6)
|
9 (0.8)
|
7 (1.0)
|
1 (0.4)
|
0 (0.0)
|
|
Isolated head injury
|
180 (2.4)
|
10 (3.1)
|
29 (3.8)
|
43 (2.5)
|
30 (2.1)
|
20 (1.8)
|
29 (2.6)
|
13 (1.8)
|
4 (1.6)
|
2 (4.7)
|
|
Other
|
929 (12.4)
|
53 (16.6)
|
109 (14.4)
|
250 (14.5)
|
186 (12.9)
|
128 (11.7)
|
107 (9.5)
|
71 (9.7)
|
24 (9.8)
|
1 (2.3)
|
|
NIV (n, %)
|
1854 (24.8)
|
71 (22.3)
|
155 (20.5)
|
383 (22.2)
|
375 (25.9)
|
298 (27.2)
|
306 (27.2)
|
200 (27.4)
|
53 (21.5)
|
13 (30.2)
|
|
Intubation (n, %)
|
3804 (50.8)
|
165 (51.7)
|
421 (55.7)
|
885 (51.4)
|
731 (50.6)
|
510 (46.5)
|
551 (48.9)
|
357 (48.9)
|
159 (64.6)
|
25 (58.1)
|
|
Vasoactive drugs (n, %)
|
4400 (58.8)
|
173 (54.2)
|
436 (57.7)
|
1004 (58.3)
|
837 (57.9)
|
646 (58.9)
|
677 (60.1)
|
436 (59.7)
|
162 (65.9)
|
29 (67.4)
|
|
Renal replacement therapy (n, %)
|
820 (11.0)
|
24 (7.5)
|
72 (9.5)
|
208 (12.1)
|
165 (11.4)
|
101 (9.2)
|
126 (11.2)
|
76 (10.4)
|
43 (17.5)
|
5 (11.6)
|
|
Life sustaining treatment limitation
|
|
None
|
4930 (65.8)
|
239 (74.9)
|
571 (75.5)
|
1236 (71.7)
|
982 (67.9)
|
688 (62.7)
|
669 (59.4)
|
370 (50.7)
|
154 (62.6)
|
21 (48.8)
|
|
Withdrawal
|
1108 (14.8)
|
39 (12.2)
|
107 (14.2)
|
234 (13.6)
|
194 (13.4)
|
166 (15.1)
|
183 (16.2)
|
135 (18.5)
|
39 (15.9)
|
11 (25.6)
|
|
Withholding
|
1449 (19.4)
|
41 (12.9)
|
78 (10.3)
|
253 (14.7)
|
270 (18.7)
|
243 (22.2)
|
275 (24.4)
|
225 (30.8)
|
53 (21.5)
|
11 (25.6)
|
|
Length of stay in the ICU, days, non-survivors (median [IQR])
|
3.00 [1.00, 7.93]
|
5.10 [1.87, 0.82]
|
3.00 [0.67, 8.85]
|
3.30 [1.00, 8.00]
|
3.80 [1.10, 9.00]
|
2.50 [1.00, 7.20]
|
3.00 [1.00, 7.00]
|
2.20 [0.80, 6.05]
|
3.00 [1.00, 8.20]
|
2.30 [0.80, 5.47]
|
|
Length of stay in the ICU, days, survivors (median [IQR])
|
3.30 [1.70, 7.00]
|
3.80 [1.80, 8.00]
|
3.50 [1.80, 6.93]
|
3.60 [1.80, 7.82]
|
3.50 [1.70, 7.00]
|
3.15 [1.50, 6.53]
|
3.00 [1.60, 6.23]
|
3.00 [1.35, 6.25]
|
6.20 [2.00,15.00]
|
3.70 [1.00,12.50]
|
|
Death in the ICU (n, %)
|
2024 (27.0)
|
60 (18.8)
|
188 (24.9)
|
403 (23.4)
|
369 (25.5)
|
273 (24.9)
|
331 (29.4)
|
259 (35.5)
|
113 (45.9)
|
28 (65.1)
|
|
Death in 30-day follow-up (n, %)
|
2985 (39.9)
|
91 (28.5)
|
254 (33.6)
|
576 (33.4)
|
545 (37.7)
|
416 (37.9)
|
513 (45.5)
|
406 (55.6)
|
149 (60.6)
|
35 (81.4)
|
