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Table 1 Summary of the included studies: general characteristics of the enrolled population

From: Perioperative liberal versus restrictive fluid strategies and postoperative outcomes: a systematic review and metanalysis on randomised-controlled trials in major abdominal elective surgery

References

Year

Pt. analysed

n (%)

RES

n (%)

LIB

n (%)

Age

(years)

BMI

(kg/m2)

ASA I, n (%)

ASA II, n (%)

ASA III–IV, n (%)

RES

LIB

RES

LIB

RES

LIB

RES

LIB

RES

LIB

Brandstrup [46]

2003

141

69 (48.9)

72 (51.1)

64

69

25

25

34 (49.3)

32 (44.4)

33 (47.8)

39 (54.2)

2 (2.9)

1 (1.4)

Kabon [26]

2005

253

124 (49)

129 (51)

53

52

NA

NA

13 (10.5)

9 (7.0)

81 (65.3)

86 (66.7)

30 (24.2)

34 (26.4)

Nisanevich [28]

2005

152

77 (50.7)

75 (49.3)

63

59

26

25

15 (19.5)

19 (25.3)

42 (54.5)

37 (49.3)

20 (26)

19 (25.3)

Holte [39]

2007

32

16 (50)

16 (50)

74

77

26

24

5 (31.2)

3 (18.8)

2 (12.5)

5 (31.2)

8 (50)

9 (56.2)

Muller [37]

2009

151

76 (50.3)

75 (49.7)

62

59

24

26

2 (2.6)

3 (4.0)

50 (65.8)

54 (72)

24 (31.6)

18 (24)

Futier [36]

2010

70

36 (51.4)

34 (48.6)

62

60

25

24

19 (52.8)

20 (58.8)

9 (25)

6 (17.6)

8 (22.2)

7 (20.6)

Gao [30]

2012

179

93 (52)

86 (48)

72

73

22

22

33 (35.5)

32 (37.2)

27 (29)

24 (27.9)

33 (35.5)

30 (34.9)

Matot [25]

2012

107

52 (48.6)

55 (51.4)

40

42

44

43

0 (0.0)

0 (0.0)

33 (63.5)

38 (69.1)

19 (36.5)

17 (30.9)

Abraham [38]

2012

161

82 (50.9)

79 (49.1)

68

69

25

25

19 (23.1)

21 (26.6)

49 (59.7)

53 (67.1)

11 (14.4)

8 (10.1)

Kalyan [32]

2013

239

121 (50.6)

118 (49.4)

70

70

26

26

28 (23.1)

17 (14.4)

70 (57.9)

75 (63.6)

23 (19.0)

26 (22.0)

Lavu [33]

2014

250

131 (52.4)

128 (51.2)

67

68

27

25

NA

NA

NA

NA

83 (63.4)

84 (65.6)

Hong-Ying [49]

2014

185

89 (48.1)

96 (51.9)

65

65

22

22

29 (32.6)

30 (31.3)

37 (41.6)

41 (42.7)

23 (25.8)

25 (26)

Piljic [34]

2015

60

30 (50)

30 (50)

69

69

25

25

NA

NA

NA

NA

NA

NA

van Samkar [47]

2015

54

30 (55.6)

24 (44.4)

NA

NA

NA

NA

NA

NA

NA

NA

NA

NA

Grant [31]

2016

330

166 (50.3)

164 (49.7)

65

65

26

27

7 (4.2)

6 (3.7)

88 (53)

90 (54.9)

71 (42.8)

68 (41.5)

Kassim [29]

2016

50

25 (50)

25 (50)

67

66

NA

NA

NA

NA

NA

NA

NA

NA

Myles [16]

2018

2983

1490 (49.9)

1493 (50.1)

66

66

NA

NA

25 (1.7)

21 (1.4)

542 (36.4)

540 (36.2)

923 (61.9)

932 (62.4)

Wuethrich [35]

2014

166

83 (50.0)

83 (50.0)

69

68

24

24

0 (0.0)

0 (0.0)

52 (63)

46 (55)

31 (37)

37 (45)

  1. N: number of patients; NA: data not available; ASA: American Society of Anaesthesiologists physical status; RES/LIB refers to those patients who received restrictive or liberal strategy, respectively. Age and body mass index (BMI) columns report the mean/median values of the LIB/RES populations recorded in each study