Table 3 Renal variables
Placebo (n = 13) | Levosimendan (n = 16) | Between group difference (LMM) | |||
|---|---|---|---|---|---|
Variable | Pre | Post | Pre | Post | p value |
Renal blood flow (L/min) | 441 ± 159 | 455 ± 166 | 327 ± 148 | 375 ± 156 *** | 0.011 |
Glomerular filtration rate (ml/min) | 63.7 ± 19.7 | 63.8 ± 18.9 | 47.9 ± 15.2 | 50.0 ± 16.1 | 0.440 |
Renal prefusion pressure (mmHg) | 70.3 ± 12.9 | 69.1 ± 7.3 | 66.0 ± 7.1 | 64.0 ± 5.5 | 0.907 |
Renal vascular resistance (mmHg/mL/min) | 0.178 ± 0.067 | 0.170 ± 0.061 | 0.253 ± 0.131 | 0.208 ± 0.104** | 0.043 |
Diuresis (ml/min) | 1.89 ± 1.07 | 1.83 ± 0.61 | 1.71 ± 0.87 | 1.82 ± 0.96 | 0.637 |
Filtration fraction | 0.104 ± 0.026 | 0.101 ± 0.018 | 0.117 ± 0.044 | 0.104 ± 0.034** | 0.056 |