Placebo (n = 13) | Levosimendan (n = 16) | Between group difference (LMM) | |||
---|---|---|---|---|---|
Variable | Pre | Post | Pre | Post | p value |
Central venous oxygen saturation (%) | 66.1 ± 6.6 | 64.9 ± 4.4 | 67.1 ± 7.4 | 68.0 ± 6.4 | 0.402 |
Arterial oxygen saturation (%) | 95.4 ± 1.1 | 95.3 ± 1.2 | 95.6 ± 2.0 | 95.2 ± 1.8 | 0.655 |
Mean arterial pressure (mmHg) | 79.6 ± 11.8 | 80.0 ± 6.6 | 74.8 ± 9.2 | 71.7 ± 4.5 | 0.362 |
Central venous pressure (mmHg) | 9.3 ± 4.3 | 11.0 ± 3.9 * | 7.3 ± 4.3 | 7.5 ± 4.3 | 0.141 |
Body temperature (°C) | 37.3 ± 0.5 | 37.4 ± 0.6 | 37.1 ± 0.7 | 37.2 ± 0.7 | 0.454 |
Norepinephrine dose (µg/kg/min) | 0.031 ± 0.046 | 0.022 ± 0.030 | 0.054 ± 0.059 | 0.098 ± 0.113 * | 0.012 |
Heart rate (beats/min) | 83.2 ± 11.7 | 85.0 ± 12.0 | 78.6 ± 9.1 | 83.1 ± 12.6 * | 0.250 |
Erythrocyte volume fraction | 0.32 ± 0.04 | 0.31 ± 0.04 * | 0.30 ± 0.03 | 0.30 ± 0.03 | 0.446 |